TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.0240nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells coexpressing Galpha protein 16z25 assessed as increase in calcium mobilization measured...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.0500nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells coexpressing Galpha protein 16z25 assessed as increase in calcium mobilization measured...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.0500nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.0600nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.0690nMAssay Description:Agonist activity at human melatonin receptor-2 transfected in CHO cell membranes after 1 hr by GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.0700nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.0900nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.0900nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.0960nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.100nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.100nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.100nMAssay Description:Agonist activity at human human MT2 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.100nMAssay Description:Agonist potency determined by [35S]-GTP gamma-S binding assay using CHO cell lines for Melatonin receptor type 1BMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.110nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells coexpressing Galpha protein 16z25 assessed as increase in calcium mobilization measured...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.170nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.180nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.180nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.180nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.190nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.200nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.200nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.200nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.200nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.200nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.200nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells coexpressing Galpha protein 16z25 assessed as increase in calcium mobilization measured...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.210nMAssay Description:Agonist activity at human MT2 expressed in CHO cell membrane incubated for 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.240nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells coexpressing Galpha protein 16z25 assessed as increase in calcium mobilization measured...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.260nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.270nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.350nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.390nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.400nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.400nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.410nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.420nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.470nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.490nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.490nMAssay Description:Agonist potency determined by [35S]-GTP gamma-S binding assay using CHO cell lines for Melatonin receptor type 1BMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.490nMAssay Description:Agonist activity at human human MT2 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.510nMAssay Description:Agonist activity at human MT2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 30 mins by AlphaS...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.520nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.530nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as decrease in forskolin-stimulated cAMP release after 30 mins by multilabel p...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.560nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.600nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Hong Kong University of Science and Technology
Curated by ChEMBL
Hong Kong University of Science and Technology
Curated by ChEMBL
Affinity DataEC50: 0.640nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair