Compile Data Set for Download or QSAR
Found 250 of ec50 for UniProtKB: P36897
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50238071(CHEMBL4079857)copy SMILEScopy InChI
Affinity DataEC50:  6.30nMAssay Description:Inhibition of ALK5 (unknown origin) expressed in SBE-bla HEK293T cells assessed as decrease in TGFbeta1-induced Smad2/3 phosphorylation by beta lacta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KKZPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50238072(CHEMBL4104104)copy SMILEScopy InChI
Affinity DataEC50:  7.90nMAssay Description:Binding affinity against cytidine deaminase of mouse kidneyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KKZPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50238082(CHEMBL4102696)copy SMILEScopy InChI
Affinity DataEC50:  7.90nMAssay Description:Inhibition of ALK5 (unknown origin) expressed in SBE-bla HEK293T cells assessed as decrease in TGFbeta1-induced Smad2/3 phosphorylation by beta lacta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KKZPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50238084(CHEMBL4085333)copy SMILEScopy InChI
Affinity DataEC50:  7.90nMAssay Description:Concentration required for 50% inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KKZPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346302(US10202377, Compound 202)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346308(US10202377, Compound 234)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346313(US10202377, Compound 265)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346314(US10202377, Compound 268)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346316(US10202377, Compound 271)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346317(US10202377, Compound 277)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346319(US10202377, Compound 283)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346320(US10202377, Compound 288)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346321(US10202377, Compound 292)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346322(US10202377, Compound 294)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346324(US10202377, Compound 298)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346333(US10202377, Compound 325)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346336(US10202377, Compound 337)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346341(US10202377, Compound 367)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346343(US10202377, Compound 379)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346351(US10202377, Compound 421)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346353(US10202377, Compound 427)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346354(US10202377, Compound 433)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346356(US10202377, Compound 439)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346357(US10202377, Compound 442)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346358(US10202377, Compound 448)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346365(US10202377, Compound 939)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346379(US10202377, Compound 953)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346383(US10202377, Compound 1350)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346269(US10202377, Compound 1)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346271(US10202377, Compound 13)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346279(US10202377, Compound 55)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346283(US10202377, Compound 82)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346285(US10202377, Compound 90)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346286(US10202377, Compound 93)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346287(US10202377, Compound 101)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346294(US10202377, Compound 154)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346296(US10202377, Compound 169)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346298(US10202377, Compound 181)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346300(US10202377, Compound 190)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346301(US10202377, Compound 196)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533226(CHEMBL4467267)copy SMILEScopy InChI
Affinity DataEC50:  9.10nMAssay Description:Inhibition of ALK5 in TGF beta1-stimulated HEK293T cells by SMAD binding element-driven beta lactamase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NQTPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533226(CHEMBL4467267)copy SMILEScopy InChI
Affinity DataEC50:  9.10nMAssay Description:Inhibition of ALK5 in TGF beta1-stimulated HEK293T cells by SMAD binding element-driven beta lactamase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NQTPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533223(CHEMBL4470706)copy SMILEScopy InChI
Affinity DataEC50:  9.5nMAssay Description:Inhibition of ALK5 in TGF beta1-stimulated HEK293T cells by SMAD binding element-driven beta lactamase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NQTPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533223(CHEMBL4470706)copy SMILEScopy InChI
Affinity DataEC50:  9.5nMAssay Description:Inhibition of ALK5 in TGF beta1-stimulated HEK293T cells by SMAD binding element-driven beta lactamase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NQTPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346272(US10202377, Compound 20)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50238070(CHEMBL4069101)copy SMILEScopy InChI
Affinity DataEC50:  13nMAssay Description:Inhibition of ALK5 (unknown origin) expressed in SBE-bla HEK293T cells assessed as decrease in TGFbeta1-induced Smad2/3 phosphorylation by beta lacta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KKZPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346342(US10202377, Compound 373)copy SMILEScopy InChI
Affinity DataEC50:  14nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50238095(CHEMBL4082868)copy SMILEScopy InChI
Affinity DataEC50:  16nMAssay Description:Inhibition of ALK5 (unknown origin) expressed in SBE-bla HEK293T cells assessed as decrease in TGFbeta1-induced Smad2/3 phosphorylation by beta lacta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KKZPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50533228(CHEMBL4452818)copy SMILEScopy InChI
Affinity DataEC50:  17nMAssay Description:Inhibition of ALK5 in TGF beta1-stimulated HEK293T cells by SMAD binding element-driven beta lactamase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NQTPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM346270(US10202377, Compound 7)copy SMILEScopy InChI
Affinity DataEC50:  17nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639RV7US Patent
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