Compile Data Set for Download or QSAR
Found 276 of ec50 for UniProtKB: P0C6X1
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM648427(US20240033256, Compound 2)copy SMILES
Affinity DataEC50:  6.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM50281169(CHEMBL4173846 | US20240034730, Compound 1)copy SMILEScopy InChI
Affinity DataEC50:  22nMMore data for this Ligand-Target Pair
In DepthDetails
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)copy SMILEScopy InChI
Affinity DataEC50:  22nMMore data for this Ligand-Target Pair
In DepthDetails
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM648428(US20240033256, Compound 3)copy SMILES
Affinity DataEC50:  25.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM429505(Remdesivir | US20240034730, Compound Remdesivir | ...)copy SMILEScopy InChI
Affinity DataEC50:  35nMMore data for this Ligand-Target Pair
In DepthDetails
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM648426(US20240033256, Compound 1)copy SMILES
Affinity DataEC50:  71.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM655509(US11912714, Example 6)copy SMILES
Affinity DataEC50: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM655508(US11912714, Example 5)copy SMILES
Affinity DataEC50: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM655506(US11912714, Example 3 | US11912714, Example 4)copy SMILES
Affinity DataEC50: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM655504(US11912714, Example 1)copy SMILES
Affinity DataEC50: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM484195(UAWJ9-36-3)copy SMILEScopy InChI
Affinity DataEC50:  130nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8GWQPubMed
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM484194(UAWJ9-36-1)copy SMILEScopy InChI
Affinity DataEC50:  170nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8GWQPubMed
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM448319(GC-376 | GC376)copy SMILEScopy InChI
Affinity DataEC50:  230nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8GWQPubMed
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM655514(US11912714, Example 11)copy SMILES
Affinity DataEC50:  550nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM655505(US11912714, Example 2)copy SMILES
Affinity DataEC50:  550nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM655506(US11912714, Example 3 | US11912714, Example 4)copy SMILES
Affinity DataEC50:  550nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM476337(US10874687, Compound 1A)copy SMILEScopy InChI
Affinity DataEC50:  1.60E+3nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9238US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM476337(US10874687, Compound 1A)copy SMILEScopy InChI
Affinity DataEC50:  2.00E+3nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9238US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM496896(US11312704, Compound 101 | US11351149, Example 49 ...)copy SMILEScopy InChI
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509781(US11124497, Compound 103 | US11312704, Compound 10...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509782(US11124497, Compound 127 | US11124497, Compound 13...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509786(US11124497, Compound 134 | US11472793, Compound 13...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM576978(US11472793, Compound 134 (Isomer 1))copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM576979(US11472793, Compound 134 (Isomer 2) | US11472793, ...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509789(US11124497, Compound 135 | US11312704, Compound 13...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM576979(US11472793, Compound 134 (Isomer 2) | US11472793, ...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509800(US11124497, Compound 171 | US11312704, Compound 17...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509802(US11124497, Compound 185 | US11312704, Compound 18...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509803(US11124497, Compound 197 | US11312704, Compound 19...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509805(US11124497, Compound 205 | US11312704, Compound 20...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM577023(US11472793, Compound 323 (Isomer 1))copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM577024(US11472793, Compound 323 (Isomer 2))copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM550864(US11312704, Compound 329 | US11472793, Compound 32...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509837(US11124497, Compound 331 (Isomer 1) | US11312704, ...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509838(US11124497, Compound 331 (Isomer 2) | US11312704, ...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509839(US11124497, Compound 344D | US11312704, Compound 3...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509840(US11124497, Compound 344C | US11312704, Compound 3...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509841(US11124497, Compound 344A | US11312704, Compound 3...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509842(US11124497, Compound 345 | US11312704, Compound 34...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM577034(US11472793, Compound 345 (Isomer 1))copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509842(US11124497, Compound 345 | US11312704, Compound 34...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509848(US11124497, Compound 361 | US11312704, Compound 36...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509849(US11124497, Compound 363 | US11312704, Compound 36...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509854(US11124497, Compound 375A | US11312704, Compound 3...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509855(US11124497, Compound 377 | US11312704, Compound 37...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509856(US11124497, Compound 379 | US11312704, Compound 37...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509858(US11124497, Compound 385 (Isomer 1) | US11312704, ...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509859(US11124497, Compound 385 (Isomer 2) | US11312704, ...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM577052(US11472793, Compound 389A (Isomer 1) | US11524940,...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)TBA
LigandPNGBDBM509863(US11124497, Compound 393 | US11312704, Compound 39...)copy SMILES
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56P00US Patent
Displayed 1 to 50 (of 276 total ) | Next | Last >>
Jump to: