Compile Data Set for Download or QSAR
Found 22 of ec50 for UniProtKB: P26358
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50430056(CHEMBL2336409 | SGI-1027)copy SMILEScopy InChI
Affinity DataEC50:  1.02E+4nMAssay Description:Inhibition of human His-DNMT1 using [methyl-3H]SAM as substrate after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270X8PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50239292(CHEMBL4070549)copy SMILEScopy InChI
Affinity DataEC50:  1.60E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6G1KPubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50239291(CHEMBL4091463)copy SMILEScopy InChI
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6G1KPubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50239285(CHEMBL4096869)copy SMILEScopy InChI
Affinity DataEC50:  2.40E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6G1KPubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50239288(CHEMBL4097685)copy SMILEScopy InChI
Affinity DataEC50:  2.60E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6G1KPubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50239289(CHEMBL4096752)copy SMILEScopy InChI
Affinity DataEC50:  2.70E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6G1KPubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50239293(CHEMBL4076088)copy SMILEScopy InChI
Affinity DataEC50:  3.00E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6G1KPubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50239286(CHEMBL4084601)copy SMILEScopy InChI
Affinity DataEC50:  3.20E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6G1KPubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50239284(CHEMBL4096360)copy SMILEScopy InChI
Affinity DataEC50:  4.60E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6G1KPubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50239287(CHEMBL4100095)copy SMILEScopy InChI
Affinity DataEC50:  7.30E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6G1KPubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50506776(CHEMBL4442279)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5J76PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50506774(CHEMBL4470149)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5J76PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50506782(CHEMBL4461581)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5J76PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50506783(CHEMBL4582042)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5J76PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50239290(CHEMBL4099197)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+5nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6G1KPubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50506785(CHEMBL4537137)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5J76PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50506786(CHEMBL4469152)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5J76PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50506787(CHEMBL4558658)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5J76PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50506789(CHEMBL4470318)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5J76PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50506788(CHEMBL4526979)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5J76PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50506790(CHEMBL4574840)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5J76PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£ de Service et de Recherche CNRS-Pierre Fabre n£3388

Curated by ChEMBL
LigandPNGBDBM50506784(CHEMBL4527662)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5J76PubMed