Compile Data Set for Download or QSAR
Found 43 of ic50 for UniProtKB: P03366
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM17667(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M6409PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM17666(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M6409PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM17665(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)copy SMILEScopy InChI
Affinity DataIC50: 200nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM17672(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)copy SMILEScopy InChI
Affinity DataIC50: 280nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M6409PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM17668(CHEMBL58494 | N-[2-(2,6-difluorophenyl)-1-[(2,6-di...)copy SMILEScopy InChI
Affinity DataIC50: 320nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M6409PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM17673(4-bromo-2-(2,6-difluorophenyl)-1-[(2,6-difluorophe...)copy SMILEScopy InChI
Affinity DataIC50: 1.61E+3nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M6409PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM17670(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)copy SMILEScopy InChI
Affinity DataIC50: 1.88E+3nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M6409PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM33045(2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophe...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P300FPubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM17674(4-chloro-2-(2,6-difluorophenyl)-1-[(2,6-difluoroph...)copy SMILEScopy InChI
Affinity DataIC50: 2.63E+3nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M6409PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM33963(vinylogous urea, NSC727448)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P300FPubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16189(4-(3-Iodophenyl)-3-oxobutanenitrile | beta-ketonit...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16185(3-(3-Chlorophenyl)-3-oxopropanenitrile | beta-keto...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM17676(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)copy SMILEScopy InChI
Affinity DataIC50: 4.94E+3nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M6409PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16187(3-(3-benzoylphenyl)-3-oxopropanenitrile | 3-Benzoy...)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+3nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16196(4-(3-Bromo-4-chlorophenyl)-1H-imidazole-5-carboxam...)copy SMILEScopy InChI
Affinity DataIC50: 9.90E+3nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16208(4-(3-Benzoylphenyl)thiazole-5-carboxamide | 4-(3-b...)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM17669(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+4nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M6409PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16191(3-(3-Iodophenyl)-3-oxopropanamide | beta-ketoamide...)copy SMILEScopy InChI
Affinity DataIC50: 2.96E+4nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16188(3-Phenyl-3-oxopropanenitrile | 3-oxo-3-(3-phenylph...)copy SMILEScopy InChI
Affinity DataIC50: 3.34E+4nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM17677(2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)meth...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M6409PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16203(2-Amino-4-(3-benzoylphenyl)thiazole-5-carboxamide ...)copy SMILEScopy InChI
Affinity DataIC50: 4.41E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16201(2-Amino-4-(3-chlorophenyl)thiazole-5-carboxamide |...)copy SMILEScopy InChI
Affinity DataIC50: 5.44E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM17675(CHEMBL58358 | N-[2-(2,6-difluorophenyl)-1-[(2,6-di...)copy SMILEScopy InChI
Affinity DataIC50: 5.47E+4nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M6409PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16204(2-Amino-4-(3-phenylphenyl)thiazole-5-carboxamide |...)copy SMILEScopy InChI
Affinity DataIC50: 5.92E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16190(3-(2-Cyanoacetyl)phenyl Diethyl Phosphate | [3-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 6.43E+4nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16195(4-(3-Chlorophenyl)-1H-imidazole-5-carboxamide | Im...)copy SMILEScopy InChI
Affinity DataIC50: 7.98E+4nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16205(2-Amino-4-phenylthiazole-5-carboxamide | 2-amino-4...)copy SMILEScopy InChI
Affinity DataIC50: 8.07E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16207(4-(3-Bromo-4-chlorophenyl)thiazole-5-carboxamide |...)copy SMILEScopy InChI
Affinity DataIC50: 8.75E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16202(2-Amino-4-(3-bromo-4-chlorophenyl)thiazole-5-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+5nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16200(2-Amino-4-(3-iodophenyl)thiazole-5-carboxamide | 2...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+5nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM17671(benzimidazole analogue, 50 | methyl 2-(2,6-difluor...)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+5nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M6409PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16210(4-Phenylthiazole-5-carboxamide | 4-phenyl-1,3-thia...)copy SMILEScopy InChI
Affinity DataIC50: 2.83E+5nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16199(4-Phenyl-1H-imidazole-5-carboxamide | Imidazole 8g)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16206(4-(3-Iodophenyl)thiazole-5-carboxamide | 4-(3-iodo...)copy SMILEScopy InChI
Affinity DataIC50: 3.12E+5nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16197(4-(3-Benzoylphenyl)-1H-imidazole-5-carboxamide | I...)copy SMILEScopy InChI
Affinity DataIC50: 3.12E+5nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16193(3-(3-Benzoylphenyl)-3-oxopropanamide | beta-ketoam...)copy SMILEScopy InChI
Affinity DataIC50: 3.12E+5nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16209(4-(3-Phenylphenyl)thiazole-5-carboxamide | 4-(3-ph...)copy SMILEScopy InChI
Affinity DataIC50: 3.12E+5nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16184(3-(3-Iodophenyl)-3-oxopropanenitrile | beta-ketoni...)copy SMILEScopy InChI
Affinity DataIC50: 3.12E+5nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16186(3-(3-Bromo-4-chlorophenyl)-3-oxopropanenitrile | b...)copy SMILEScopy InChI
Affinity DataIC50: 3.12E+5nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16198(4-(3-Phenylphenyl)-1H-imidazole-5-carboxamide | Im...)copy SMILEScopy InChI
Affinity DataIC50: 3.12E+5nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16192(3-(3-Chlorophenyl)-3-oxopropanamide | beta-ketoami...)copy SMILEScopy InChI
Affinity DataIC50: 3.12E+5nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
NCI-FCRDC

LigandPNGBDBM16194(3-Oxo-3-(3-phenylphenyl)propanamide | beta-ketoami...)copy SMILEScopy InChI
Affinity DataIC50: 3.12E+5nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM49J0PubMed