Compile Data Set for Download or QSAR
Found 1063 of ic50 for UniProtKB: P50613
LigandPNGBDBM50539763(Adagrasib | Mrtx-849 | Mrtx849)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6W53PubMed
LigandPNGBDBM530357(WO2022064009, Compound 136 | WO2022064009, Compoun...)copy SMILES
Affinity DataIC50: 1.38nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530269(WO2022064009, Compound 13)copy SMILES
Affinity DataIC50: 1.41nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530396(WO2022064009, Compound 173)copy SMILES
Affinity DataIC50: 1.66nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530309(WO2022064009, Compound 70)copy SMILES
Affinity DataIC50: 1.78nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530370(WO2022064009, Compound 180a)copy SMILES
Affinity DataIC50: 2.09nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530318(WO2022064009, Compound 82 | WO2022064009, Compound...)copy SMILES
Affinity DataIC50: 2.14nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530249(WO2022064009, Compound 5)copy SMILES
Affinity DataIC50: 2.14nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530318(WO2022064009, Compound 82 | WO2022064009, Compound...)copy SMILES
Affinity DataIC50: 2.14nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530297(WO2022064009, Compound 58)copy SMILES
Affinity DataIC50: 2.34nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530245(WO2022064009, Compound 1 | WO2022064009, Compound ...)copy SMILES
Affinity DataIC50: 2.45nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530266(WO2022064009, Compound 154 | WO2022064009, Compoun...)copy SMILES
Affinity DataIC50: 2.51nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530260(WO2022064009, Compound 37)copy SMILES
Affinity DataIC50: 2.51nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530397(WO2022064009, Compound 174)copy SMILES
Affinity DataIC50: 2.63nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530383(WO2022064009, Compound 160)copy SMILES
Affinity DataIC50: 2.63nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530308(WO2022064009, Compound 69)copy SMILES
Affinity DataIC50: 2.69nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530252(WO2022064009, Compound 8)copy SMILES
Affinity DataIC50: 2.69nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530305(WO2022064009, Compound 66)copy SMILES
Affinity DataIC50: 2.75nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530280(WO2022064009, Compound 29)copy SMILES
Affinity DataIC50: 2.82nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530401(WO2022064009, Compound 188)copy SMILES
Affinity DataIC50: 2.82nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530310(WO2022064009, Compound 71)copy SMILES
Affinity DataIC50: 2.88nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM50363196(CHEMBL1944698)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged CDK7/cyclin H/N-terminal GST-tagged MAT1 expressed in baculovirus infected Sf21 in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73GP8PubMed
LigandPNGBDBM530335(WO2022064009, Compound 120 | WO2022064009, Compoun...)copy SMILES
Affinity DataIC50: 3.02nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530369(WO2022064009, Compound 150)copy SMILES
Affinity DataIC50: 3.16nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530356(WO2022064009, Compound 134)copy SMILES
Affinity DataIC50: 3.16nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530337(WO2022064009, Compound 122b)copy SMILES
Affinity DataIC50: 3.16nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530286(WO2022064009, Compound 156 | WO2022064009, Compoun...)copy SMILES
Affinity DataIC50: 3.24nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530256(WO2022064009, Compound 12)copy SMILES
Affinity DataIC50: 3.24nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530424(WO2022064009, Compound 210)copy SMILES
Affinity DataIC50: 3.31nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530423(WO2022064009, Compound 209)copy SMILES
Affinity DataIC50: 3.31nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530299(WO2022064009, Compound 60)copy SMILES
Affinity DataIC50: 3.55nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530354(WO2022064009, Compound 132)copy SMILES
Affinity DataIC50: 3.63nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530339(WO2022064009, Compound 126)copy SMILES
Affinity DataIC50: 3.72nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530250(WO2022064009, Compound 6)copy SMILES
Affinity DataIC50: 3.80nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530316(WO2022064009, Compound 78)copy SMILES
Affinity DataIC50: 4.27nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530377(WO2022064009, Compound 152)copy SMILES
Affinity DataIC50: 4.37nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530251(WO2022064009, Compound 7)copy SMILES
Affinity DataIC50: 4.47nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530301(WO2022064009, Compound 62 | WO2022064009, Compound...)copy SMILES
Affinity DataIC50: 4.68nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530426(WO2022064009, Compound 212)copy SMILES
Affinity DataIC50: 4.79nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530408(WO2022064009, Compound 195b)copy SMILES
Affinity DataIC50: 4.90nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530342(WO2022064009, Compound 129)copy SMILES
Affinity DataIC50: 4.90nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530247(WO2022064009, Compound 3)copy SMILES
Affinity DataIC50: 5.01nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530262(WO2022064009, Compound 39)copy SMILES
Affinity DataIC50: 5.01nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530286(WO2022064009, Compound 156 | WO2022064009, Compoun...)copy SMILES
Affinity DataIC50: 5.01nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530293(WO2022064009, Compound 54)copy SMILES
Affinity DataIC50: 5.13nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530298(WO2022064009, Compound 59)copy SMILES
Affinity DataIC50: 5.25nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530410(WO2022064009, Compound 199)copy SMILES
Affinity DataIC50: 5.37nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530414(WO2022064009, Compound 203)copy SMILES
Affinity DataIC50: 5.37nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530312(WO2022064009, Compound 73)copy SMILES
Affinity DataIC50: 5.75nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
LigandPNGBDBM530394(WO2022064009, Compound 171a)copy SMILES
Affinity DataIC50: 5.75nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC936BPubMed
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