Compile Data Set for Download or QSAR
Found 64 of ic50 for UniProtKB: P14867
LigandPNGBDBM50290077(CHEMBL73416 | N-[2-(4-Chloro-phenyl)-imidazo[1,2-a...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Compound was evaluated for in vitro functional inhibitory potency for prevention of ET-1 induced constriction of rat aortic rings (ETA receptors)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CB0
LigandPNGBDBM50290077(CHEMBL73416 | N-[2-(4-Chloro-phenyl)-imidazo[1,2-a...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:In vitro functional inhibitory potency prevention of ET-1 induced constriction of rat aortic rings (ETB receptors)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CB0
LigandPNGBDBM50483961(CHEMBL1795561)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human recombinant GABA A receptor alpha1beta2gamma2S expressed in HEK293 cells assessed as inhibition of GABA-induced current ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR5101PubMed
LigandPNGBDBM50483959(CHEMBL1795560)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Antagonist activity at human recombinant GABA A receptor alpha1beta2gamma2S expressed in HEK293 cells assessed as inhibition of GABA-induced current ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR5101PubMed
LigandPNGBDBM50537125(CHEMBL1851667)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA(A) receptor expressed in human tsA201 cells assessed as inhibition of GABA-induced membrane pote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2225VPubMed
LigandPNGBDBM50483958(CHEMBL1795348)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human recombinant GABA A receptor alpha1beta2gamma2S expressed in HEK293 cells assessed as inhibition of GABA-induced current ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR5101PubMed
LigandPNGBDBM50378769(CHEMBL1204074)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA(A) receptor expressed in human tsA201 cells assessed as inhibition of GABA-induced membrane pote...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2225VPubMed
LigandPNGBDBM50378769(CHEMBL1204074)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VFMPubMed
LigandPNGBDBM50483960(CHEMBL1795562)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Antagonist activity at human recombinant GABA A receptor alpha1beta2gamma2S expressed in HEK293 cells assessed as inhibition of GABA-induced current ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR5101PubMed
LigandPNGBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Compound was evaluated for in vitro functional inhibitory potency for prevention of ET-1 induced constriction of rat aortic rings (ETA receptors)More data for this Ligand-Target Pair
LigandPNGBDBM50520683(CHEMBL4476621)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Displacement of [3H]muscimol from recombinant human GABAalpha1beta2gamma2 measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GNDPubMed
LigandPNGBDBM50208721(4-(biphenyl-3-yl)-5-(piperidin-4-yl)isoxazol-3-ol ...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VFMPubMed
LigandPNGBDBM50378770(CHEMBL1202335)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VFMPubMed
LigandPNGBDBM50378760(CHEMBL1202340)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VFMPubMed
LigandPNGBDBM50378763(CHEMBL1204077)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA-A receptor expressed in tsA201 cells assessed as inhibition of GABA-induced effect after 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35XKMPubMed
LigandPNGBDBM50378763(CHEMBL1204077)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA(A) receptor expressed in human tsA201 cells assessed as inhibition of GABA-induced membrane pote...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2225VPubMed
LigandPNGBDBM50378763(CHEMBL1204077)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VFMPubMed
LigandPNGBDBM50493007(CHEMBL2420450)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA-A receptor expressed in tsA201 cells assessed as inhibition of GABA-induced effect after 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35XKMPubMed
LigandPNGBDBM50493007(CHEMBL2420450)copy SMILEScopy InChI
Affinity DataIC50: 214nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA-A receptor expressed in tsA201 cells assessed as inhibition of GABA-induced effect after 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35XKMPubMed
LigandPNGBDBM50001572((gabazine)4-[6-Imino-3-(4-methoxy-phenyl)-6H-pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA-A receptor expressed in tsA201 cells assessed as inhibition of GABA-induced effect after 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35XKMPubMed
LigandPNGBDBM50001572((gabazine)4-[6-Imino-3-(4-methoxy-phenyl)-6H-pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA(A) receptor expressed in human tsA201 cells assessed as inhibition of GABA-induced membrane pote...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2225VPubMed
LigandPNGBDBM50001572((gabazine)4-[6-Imino-3-(4-methoxy-phenyl)-6H-pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 349nMAssay Description:Antagonist activity at human recombinant GABA A receptor alpha1beta2gamma2S expressed in HEK293 cells assessed as inhibition of GABA-induced current ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR5101PubMed
LigandPNGBDBM50378771(CHEMBL1204073)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VFMPubMed
LigandPNGBDBM50493006(CHEMBL2420454)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA-A receptor expressed in tsA201 cells assessed as inhibition of GABA-induced effect after 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35XKMPubMed
LigandPNGBDBM50493006(CHEMBL2420454)copy SMILEScopy InChI
Affinity DataIC50: 692nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA-A receptor expressed in tsA201 cells assessed as inhibition of GABA-induced effect after 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35XKMPubMed
LigandPNGBDBM50493003(CHEMBL2420455)copy SMILEScopy InChI
Affinity DataIC50: 780nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA-A receptor expressed in tsA201 cells assessed as inhibition of GABA-induced effect after 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35XKMPubMed
LigandPNGBDBM50378772(CHEMBL1204072)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VFMPubMed
LigandPNGBDBM50493003(CHEMBL2420455)copy SMILEScopy InChI
Affinity DataIC50: 794nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA-A receptor expressed in tsA201 cells assessed as inhibition of GABA-induced effect after 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35XKMPubMed
LigandPNGBDBM50378762(CHEMBL1202339)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VFMPubMed
LigandPNGBDBM50378764(CHEMBL1202338)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VFMPubMed
LigandPNGBDBM50095533(4-(naphthalen-2-ylmethyl)-5-(piperidin-4-yl)isoxaz...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VFMPubMed
LigandPNGBDBM50378767(CHEMBL1202337)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VFMPubMed
LigandPNGBDBM50378765(CHEMBL1204076)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VFMPubMed
LigandPNGBDBM50378766(CHEMBL1204075)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VFMPubMed
LigandPNGBDBM50378759(CHEMBL1204079)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VFMPubMed
LigandPNGBDBM50537127(CHEMBL4589563)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA(A) receptor expressed in human tsA201 cells assessed as inhibition of GABA-induced membrane pote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2225VPubMed
LigandPNGBDBM50537127(CHEMBL4589563)copy SMILEScopy InChI
Affinity DataIC50: 3.98E+3nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA(A) receptor expressed in human tsA201 cells assessed as inhibition of GABA-induced membrane pote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2225VPubMed
LigandPNGBDBM50537128(CHEMBL4586737)copy SMILEScopy InChI
Affinity DataIC50: 4.37E+3nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA(A) receptor expressed in human tsA201 cells assessed as inhibition of GABA-induced membrane pote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2225VPubMed
LigandPNGBDBM50537128(CHEMBL4586737)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA(A) receptor expressed in human tsA201 cells assessed as inhibition of GABA-induced membrane pote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2225VPubMed
LigandPNGBDBM50378761(CHEMBL1204078)copy SMILEScopy InChI
Affinity DataIC50: 8.30E+3nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VFMPubMed
LigandPNGBDBM50493004(CHEMBL2420449)copy SMILEScopy InChI
Affinity DataIC50: 9.70E+3nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA-A receptor expressed in tsA201 cells assessed as inhibition of GABA-induced effect after 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35XKMPubMed
LigandPNGBDBM50493004(CHEMBL2420449)copy SMILEScopy InChI
Affinity DataIC50: 9.77E+3nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA-A receptor expressed in tsA201 cells assessed as inhibition of GABA-induced effect after 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35XKMPubMed
LigandPNGBDBM50588340(CHEMBL5204910)copy SMILES
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49PDPubMed
LigandPNGBDBM50537129(CHEMBL4515872)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA(A) receptor expressed in human tsA201 cells assessed as inhibition of GABA-induced membrane pote...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2225VPubMed
LigandPNGBDBM50537129(CHEMBL4515872)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+4nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA(A) receptor expressed in human tsA201 cells assessed as inhibition of GABA-induced membrane pote...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2225VPubMed
LigandPNGBDBM50493005(CHEMBL2420447)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA-A receptor expressed in tsA201 cells assessed as inhibition of GABA-induced effect after 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35XKMPubMed
LigandPNGBDBM50537124(CHEMBL4570040)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA(A) receptor expressed in human tsA201 cells assessed as inhibition of GABA-induced membrane pote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2225VPubMed
Displayed 1 to 50 (of 64 total ) | Next | Last >>
Jump to: