Compile Data Set for Download or QSAR
Found 301 of ic50 for UniProtKB: P16234
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2TVTPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132388((3-Chloro-phenyl)-(6,7-dimethoxy-quinoxalin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N8796BPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039087(3-(3-Fluoro-4-methoxy-phenyl)-6,7-dimethoxy-quinol...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.003-0.005More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039073(5,7-Dimethyl-3-thiophen-3-yl-quinoline | CHEMBL304...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.001-0.005More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039041(6,7-Dimethoxy-3-((E)-styryl)-quinoline | CHEMBL701...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.001-0.005More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132386((6,7-Dimethoxy-quinoxalin-2-yl)-phenyl-amine | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N8796BPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132386((6,7-Dimethoxy-quinoxalin-2-yl)-phenyl-amine | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6JGMPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50287090(4-Chloro-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X86MF
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50175491(4-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X86MF
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50287090(4-Chloro-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348KBG
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50175491(4-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348KBG
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50026673(CHEMBL3335387)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of PDGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN39FPPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50175491(4-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2WZ9PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039071(6,7-Dimethoxy-3-(4-methoxy-phenyl)-quinoline | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.001-0.015More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132406(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-2-methyl-cy...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6JGMPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132392((+/-)Bicyclo[2.2.1]hept-2-yl-(6,7-dimethoxy-quinox...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N8796BPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039047(5-Fluoro-3-thiophen-3-yl-quinoline | CHEMBL305056)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of isolated human PDGF receptor phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039082(6,7-Dimethoxy-3-thiophen-3-yl-quinoline | CHEMBL66...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.01-0.02More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132405(5-(6,7-Dimethoxy-quinoxalin-2-ylamino)-bicyclo[2.2...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6JGMPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50404045(CHEMBL2112463)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N8796BPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039084(3-(3-Fluoro-phenyl)-6,7-dimethoxy-quinoline | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.015-0.025More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039069(7-Fluoro-3-thiophen-3-yl-quinoline | CHEMBL307093)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.004-0.025More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132409(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6JGMPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039072(3-(5-Chloro-thiophen-2-yl)-6,7-dimethoxy-quinoline...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.007-0.03More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039067(5-(6,7-Dimethoxy-quinolin-3-yl)-1H-pyridin-2-one |...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.015-0.03More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039037(4-(6,7-Dimethoxy-quinolin-3-yl)-phenol | CHEMBL303...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.02-0.03More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50118880(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Concentration required for 50% inhibition against autophosphorylation of Platelet-derived growth factor receptor beta in intact cells using a two sit...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3MXFPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50118881(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Concentration required for 50% inhibition against autophosphorylation of Platelet-derived growth factor receptor beta in intact cells using a two sit...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3MXFPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50115347(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Concentration required for 50% inhibition against autophosphorylation of Platelet-derived growth factor receptor beta in intact cells using a two sit...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3MXFPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039042(5,7-Dimethoxy-3-thiophen-3-yl-quinoline | CHEMBL66...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.025-0.03More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039090(3-Cyclopent-1-enyl-6,7-dimethoxy-quinoline | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.02-0.04More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132395((6,7-Dimethoxy-quinoxalin-2-yl)-(3-methyl-cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6JGMPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132395((6,7-Dimethoxy-quinoxalin-2-yl)-(3-methyl-cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N8796BPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132387((7-Methoxy-quinoxalin-2-yl)-phenyl-amine | CHEMBL1...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N8796BPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132409(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6JGMPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039094(6,7-Dimethoxy-3-phenylethynyl-quinoline | CHEMBL67...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.02-0.05More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X86MF
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2WZ9PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50287091(CHEMBL20252 | Naphthalene-2-carboxylic acid [4-met...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X86MF
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50287091(CHEMBL20252 | Naphthalene-2-carboxylic acid [4-met...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348KBG
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of PDGFR by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039044(3-(4-Fluoro-phenyl)-6,7-dimethoxy-quinoline | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.035-0.06More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039057(7-Methoxy-3-thiophen-3-yl-quinoline | CHEMBL68185)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.002-0.06More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132384(2-Cyclohexyloxy-6,7-dimethoxy-quinoxaline | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N8796BPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132407(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexano...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6JGMPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50118859(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Concentration required for 50% inhibition against autophosphorylation of Platelet-derived growth factor receptor beta in intact cells using a two sit...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3MXFPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039062(6,7-Dimethoxy-3-(6-methoxy-pyridin-3-yl)-quinoline...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.008-0.07More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039065(3-Benzyloxy-6,7-dimethoxy-quinoline | CHEMBL66932)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.04-0.07More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50039075(6-Methoxy-3-thiophen-3-yl-quinoline | CHEMBL303184)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.05-0.07More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93Z8PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132391(4-((R)-6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6JGMPubMed
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