Compile Data Set for Download or QSAR
Found 366 of ic50 for UniProtKB: P11802
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444543(US10662186, Compound 63 | US10988476, Compound I-6...)copy SMILEScopy InChI
Affinity DataIC50: 0.710nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50564275(CHEMBL4778367)copy SMILES
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused CDK4 (1 to 303 residues)/GST-tagged CyclinD3 (1 to 292 residues) expressed in baculo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7SHMPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444567(US10662186, Compound 86 | US10988476, Compound I-8...)copy SMILEScopy InChI
Affinity DataIC50: 0.960nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444572(US10662186, Compound 91 | US10988476, Compound I-9...)copy SMILEScopy InChI
Affinity DataIC50: 0.990nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444580(US10662186, Compound 102 | US10988476, Compound I-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444578(US10662186, Compound 98)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM642775(N-(1-(cyclopropylsulfonyl)piperidin-4-yl)-4-(diflu...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM642777(1-isopropyl-N-(1-(methylsulfonyl)piperidin-4-yl)-4...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444564(US10662186, Compound 83 | US10988476, Compound I-8...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444551(US10662186, Compound 71 | US10988476, Compound I-7...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444598(US10662186, Compound 134 | US10988476, Compound I-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444597(US10662186, Compound 133 | US10988476, Compound I-...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444585(US10662186, Compound 108 | US10988476, Compound I-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444584(US10662186, Compound 107 | US10988476, Compound I-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444591(US10662186, Compound 126 | US10988476, Compound I-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444549(US10662186, Compound 69 | US10988476, Compound I-6...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM516028(US11053238, Compound 1a | US11053238, Compound 1b)copy SMILES
Affinity DataIC50: 1.70nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959MRVUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444569(US10662186, Compound 88 | US10988476, Compound I-8...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused CDK4 (1 to 303 residues)/GST-tagged CyclinD3 (1 to 292 residues) expressed in baculo...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM516275(US11053238, Compound 15b)copy SMILES
Affinity DataIC50: 1.80nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959MRVUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM516039(US11053238, Compound 2a | US11053238, Compound 2b)copy SMILES
Affinity DataIC50: 1.90nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959MRVUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444532(US10662186, Compound 52 | US10988476, Compound I-5...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM642767(US20230416271, Compound II.21)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM515904(4-(6-fluoro-1- methyl-1,2,3,4- tetrahydrobenzo[4,5...)copy SMILES
Affinity DataIC50: 2nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959MRVUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM515905(N-(5-((4-ethylpiperazin- 1-yl)methyl) pyridin-2-yl...)copy SMILES
Affinity DataIC50: 2nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959MRVUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM515904(4-(6-fluoro-1- methyl-1,2,3,4- tetrahydrobenzo[4,5...)copy SMILES
Affinity DataIC50: 2nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959MRVUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50564275(CHEMBL4778367)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of human full-length N-terminal GST tagged CDK6 (1 to 326 residues)/GST-tagged cyclinD3 (1 to 292 residues) expressed in baculovirus expre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7SHMPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444587(US10662186, Compound 110 | US10988476, Compound I-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50564295(CHEMBL4792101)copy SMILES
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused CDK4 (1 to 303 residues)/GST-tagged CyclinD3 (1 to 292 residues) expressed in baculo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7SHMPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM444604(US10662186, Compound 140 | US10988476, Compound I-...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50564295(CHEMBL4792101)copy SMILES
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human full-length N-terminal GST tagged CDK6 (1 to 326 residues)/GST-tagged cyclinD3 (1 to 292 residues) expressed in baculovirus expre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7SHMPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50564297(CHEMBL4794123)copy SMILES
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused CDK4 (1 to 303 residues)/GST-tagged CyclinD3 (1 to 292 residues) expressed in baculo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7SHMPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50564276(CHEMBL4776781)copy SMILES
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused CDK4 (1 to 303 residues)/GST-tagged CyclinD3 (1 to 292 residues) expressed in baculo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7SHMPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM642773(4-(difluoromethyl)-1-isopropyl-N-(1-(methylsulfony...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM642774(4-(difluoromethyl)-N-(1-(ethylsulfonyl)piperidin-4...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM31539(pyrazolo[4,3-h]quinazoline-3-carboxamide, 22)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK4/Cyclin D3 (unknown origin) using FAM-labeled peptide as substrate after 40 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9KXCPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM516028(US11053238, Compound 1a | US11053238, Compound 1b)copy SMILES
Affinity DataIC50: 3nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959MRVUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM515951(US11053238, Com. EX. 5)copy SMILES
Affinity DataIC50: 3nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959MRVUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM515923(US11053238, Compound 16b | US11053238, Example 16b)copy SMILES
Affinity DataIC50: 3nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959MRVUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM642772(1-isopropyl-4-methyl-N-(1-(methylsulfonyl)piperidi...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM642760(1-isopropyl-N-(1-(methylsulfonyl)piperidin-4-yl)-1...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM642769(US20230416271, Compound II.23)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM642768(US20230416271, Compound II.22)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM642776(4-(difluoromethyl)-N-(1-((difluoromethyl)sulfonyl)...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM642779(US20230416271, Compound II.33)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM642784(N-(1-(cyclopropylsulfonyl)piperidin-4-yl)-1-isopro...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
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