Compile Data Set for Download or QSAR
Found 210 of ic50 for UniProtKB: P04775
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50223720(CHEMBL332257)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D2NPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50223731(CHEMBL118603)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D2NPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50223721(CHEMBL331513)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D2NPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50223726(CHEMBL117331)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D2NPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50223735(CHEMBL119139)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D2NPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50223734(CHEMBL331942)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D2NPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50223733(CHEMBL120306)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D2NPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50223722(CHEMBL334104)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D2NPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143966(2-Chloro-N-[2-{4-[3-(4-fluoro-phenoxy)-2-hydroxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50223723(CHEMBL119494)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D2NPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143963(CHEMBL64869 | N-[2-{4-[3-(4-Bromo-phenoxy)-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibitory concentration against [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in vitro in rat cerebral cortex membrane at ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50223725(CHEMBL118682)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D2NPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50082319((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D21Z3BPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50082324((S)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D21Z3BPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50473876(CHEMBL2112614)copy SMILEScopy InChI
Affinity DataIC50: 134nMAssay Description:Inhibitory effect against veratridine-induced glutamate release from rat brain slicesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS308ZPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50223729(CHEMBL418863)copy SMILEScopy InChI
Affinity DataIC50: 146nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D2NPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143950(CHEMBL305591 | N-Benzyl-2-{4-[3-(2,6-dimethyl-phen...)copy SMILEScopy InChI
Affinity DataIC50: 149nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143952(CHEMBL59712 | N-{1-[2-Hydroxy-3-(4-methoxy-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 183nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50082323(4-[4-(4-Fluoro-benzyl)-phenyl]-1-((E)-3-phenyl-all...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D21Z3BPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143954(CHEMBL433100 | N-(4-Fluoro-phenyl)-N-{1-[2-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 191nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143958(CHEMBL63060 | N-(4-Fluoro-phenyl)-N-{1-[2-hydroxy-...)copy SMILEScopy InChI
Affinity DataIC50: 194nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143962(CHEMBL62878 | N-(2-{4-[3-(4-Chloro-phenoxy)-2-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 208nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143964(4-Chloro-N-(4-fluoro-phenyl)-N-{1-[2-hydroxy-3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 214nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143975(2-(4-Fluoro-phenyl)-2-{4-[2-hydroxy-3-(4-methoxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 214nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50082319((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D21Z3BPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143945(4-Chloro-N-{1-[2-hydroxy-3-(4-methoxy-phenoxy)-pro...)copy SMILEScopy InChI
Affinity DataIC50: 228nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143970(CHEMBL61336 | N-(2-{4-[2-Hydroxy-3-(4-methoxy-phen...)copy SMILEScopy InChI
Affinity DataIC50: 253nMAssay Description:Inhibitory concentration against [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in vitro in rat cerebral cortex membrane at ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143957(CHEMBL60847 | N-Benzyl-2-(4-fluoro-phenyl)-2-{4-[2...)copy SMILEScopy InChI
Affinity DataIC50: 254nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50473882(CHEMBL126206)copy SMILEScopy InChI
Affinity DataIC50: 255nMAssay Description:Inhibitory effect against veratridine-induced glutamate release from rat brain slicesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS308ZPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143961(CHEMBL62240 | N-{1-[2-Hydroxy-3-(4-methoxy-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 261nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D21Z3BPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143949(CHEMBL60843 | N-Benzyl-2-{4-[3-(2,6-dimethyl-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 296nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50082320(4-(4-Phenoxy-phenyl)-1-((E)-3-phenyl-allyl)-piperi...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D21Z3BPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50473870(CHEMBL2112617)copy SMILEScopy InChI
Affinity DataIC50: 322nMAssay Description:Inhibitory effect against veratridine-induced glutamate release from rat brain slicesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS308ZPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50223732(CHEMBL118626)copy SMILEScopy InChI
Affinity DataIC50: 322nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D2NPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143967(CHEMBL60568 | N-Benzyl-2-{4-[3-(2,6-dimethyl-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 325nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143976(2-{4-[3-(2,6-Dimethyl-phenoxy)-2-hydroxy-propyl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 343nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143956(2-{4-[3-(2,6-Dimethyl-phenoxy)-2-hydroxy-propyl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 351nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143974(2-{4-[3-(2,6-Dimethyl-phenoxy)-2-hydroxy-propyl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 355nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143955(2-{4-[2-Hydroxy-3-(4-methoxy-phenoxy)-propyl]-pipe...)copy SMILEScopy InChI
Affinity DataIC50: 359nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50082322(1-{4-[4-(4-Fluoro-benzyl)-phenyl]-piperidin-1-yl}-...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D21Z3BPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143947(4-Fluoro-N-{2-[4-(2-hydroxy-3-phenoxy-propyl)-pipe...)copy SMILEScopy InChI
Affinity DataIC50: 363nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143965(CHEMBL60666 | N-(2-{4-[3-(4-Chloro-phenoxy)-2-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 363nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50473868(CHEMBL339108)copy SMILEScopy InChI
Affinity DataIC50: 379nMAssay Description:Inhibitory effect against veratridine-induced glutamate release from rat brain slicesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS308ZPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143951(1-Allyloxy-3-{4-[(4-chloro-phenyl)-phenyl-methyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 401nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143971(CHEMBL59644 | N-Benzyl-2-{4-[2-hydroxy-3-(4-methox...)copy SMILEScopy InChI
Affinity DataIC50: 429nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50473883(CHEMBL2111817)copy SMILEScopy InChI
Affinity DataIC50: 452nMAssay Description:Inhibitory effect against veratridine-induced glutamate release from rat brain slicesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS308ZPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50473869(Lifarizine | RS-87476-000)copy SMILEScopy InChI
Affinity DataIC50: 494nMAssay Description:Inhibitory effect against veratridine-induced glutamate release from rat brain slicesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS308ZPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50223728(CHEMBL119103)copy SMILEScopy InChI
Affinity DataIC50: 518nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D2NPubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50143969(CHEMBL64583 | N-(2-{4-[3-(4-Bromo-phenoxy)-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 522nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B8RPubMed
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