Compile Data Set for Download or QSAR
Found 134 of ic50 for UniProtKB: P00519
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6096(3-quinolinecarbonitrile 24 | 4-[(2,4-Dichloro-5-me...)copy SMILEScopy InChI
Affinity DataIC50: 0.780nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6094(3-quinolinecarbonitrile 18 | 4-[(2,4-Dichloro-5-me...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6095(3-quinolinecarbonitrile 23 | 4-[(2,4-Dichloro-5-me...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6102(4-[(2-Chloro-5-methoxyphenyl)amino]-6-methoxy-7-[(...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6099(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097942(3-(4-Amino-7-cyclobutyl-7H-pyrrolo[2,3-d]pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6103(4-phenylamino-3-quinolinecarbonitrile 21 | 6-Metho...)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6105(4-phenylamino-3-quinolinecarbonitrile 23 | 6-Metho...)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097956(3-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6101(3-quinolinecarbonitrile 20 | 4-phenylamino-3-quino...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6100(3-quinolinecarbonitrile 19 | 4-[(2,4-Dichloropheny...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088900(5,7-Diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine ...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of PDGF-receptor kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78DG4PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6104(4-[(2,4-Dimethylphenyl)amino]-6-methoxy-7-[(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Abl tyrosine kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097947(CHEMBL352801 | {3-[4-Amino-5-(3-methoxy-phenyl)-py...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097937(3-(4-Amino-5-phenyl-pyrrolo[2,3-d]pyrimidin-7-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088904((3-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]p...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78DG4PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097945(7-Cyclobutyl-5-(3-methoxy-phenyl)-7H-pyrrolo[2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of p60 c-Src tyrosine kinase mediated phosphorylation of Fak in IC8.1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097991(CHEMBL355019 | {3-[4-Amino-5-(3-hydroxy-phenyl)-py...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6098(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097971(CHEMBL262276 | methyl 2-(4-(4-amino-5-(3-hydroxyph...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097968(3-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2,3-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088908(5-(3-Methoxy-phenyl)-7-phenyl-7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of PDGF-receptor kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78DG4PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088909((4-(4-amino-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-7-...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Tested for inhibition of EGF-receptor tyrosine kinase in intact cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78DG4PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097951(4-(4-Amino-7-cyclobutyl-7H-pyrrolo[2,3-d]pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of p60 c-Src tyrosine kinase mediated phosphorylation of Fak in IC8.1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6097(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097936(7-Cyclobutyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097967(3-(4-amino-7-(1-(2-hydroxyethyl)piperidin-4-yl)-7H...)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Concentration required for inhibition of epidermal growth factor receptor (EGF-R) by tyrosine kinase enzyme activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7JD9PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097941(4-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097958(2-(4-(4-amino-5-(3-hydroxyphenyl)-7H-pyrrolo[2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of v-Abl receptor tyrosine kinase enzyme activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM3532(CHEMBL540068 | CHEMBL7917 | N-(3-chlorophenyl)-6,7...)copy SMILEScopy InChI
Affinity DataIC50: 125nMAssay Description:Inhibition of v-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21835PVPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097955(7-Cyclopentyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of p60 c-Src tyrosine kinase mediated phosphorylation of Fak in IC8.1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097962(2-{3-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2,3-d]p...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of autophosphorylation of epidermal growth factor receptor (EGF-R) in a cellular assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097939(7-Cyclopentyl-5-(3-methoxy-phenyl)-7H-pyrrolo[2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50132707(4-3,3-dimethyltriaz-1-ene-N-[4-methyl-3-(4-pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 195nMAssay Description:Inhibition of Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B8XFQPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088902((3-(4-amino-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-7-...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78DG4PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097979(2-(4-(4-amino-5-(3-hydroxyphenyl)-7H-pyrrolo[2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of autophosphorylation of epidermal growth factor receptor (EGF-R) in a cellular assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088898(2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78DG4PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097944(3-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of p60 c-Src tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088899(2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78DG4PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097959(7-{1-[2-(2-Methoxy-ethylamino)-ethyl]-piperidin-4-...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097954(7-Cyclopentyl-5-(4-methoxy-phenyl)-7H-pyrrolo[2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097972(3-(4-Amino-7-pyrrolidin-3-yl-7H-pyrrolo[2,3-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088903(2-((4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Tested in vitro for inhibition of EGF-receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78DG4PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097946(3-{4-Amino-7-[1-hydroxymethyl-2-(4-methoxy-phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of p60 c-Src tyrosine kinase mediated phosphorylation of Fak in IC8.1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097974(2-((2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50097938(3-(4-Amino-5-phenyl-pyrrolo[2,3-d]pyrimidin-7-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of p60 c-Src tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088913(5-(4-Methoxy-phenyl)-7-phenyl-7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78DG4PubMed
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