Compile Data Set for Download or QSAR
Found 4 of ic50 for UniProtKB: P29846
TargetGenome polyprotein [1658-1692](Hepatitis C virus)
Astex Pharmaceuticals

LigandPNGBDBM92629((3S)-3-{[(1R)-1-(4-chloro-2-fluoro-3-phenoxyphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 100nM Kd:  62nMT: 2°CAssay Description:The protease activity of the full-length NS3-NS4a and the protease domain were measured using a FRET-based assay using a peptide substrate derived fr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VVNPubMed
TargetGenome polyprotein [1658-1692](Hepatitis C virus)
Astex Pharmaceuticals

LigandPNGBDBM92628((1R)-1-(2,4-difluoro-3-phenoxyphenyl)propan-1-amin...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMT: 2°CAssay Description:The protease activity of the full-length NS3-NS4a and the protease domain were measured using a FRET-based assay using a peptide substrate derived fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VVNPubMed
TargetGenome polyprotein [1658-1692](Hepatitis C virus)
Astex Pharmaceuticals

LigandPNGBDBM92627((2,4-difluoro-3-phenoxyphenyl)methanamine, 3)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nM Kd:  2.90E+4nMT: 2°CAssay Description:The protease activity of the full-length NS3-NS4a and the protease domain were measured using a FRET-based assay using a peptide substrate derived fr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VVNPubMed
TargetGenome polyprotein [1658-1692](Hepatitis C virus)
Astex Pharmaceuticals

LigandPNGBDBM50271275(1H-Indazol-7-amine | 1H-indazol-7-amine, 1 | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+6nMT: 2°CAssay Description:The protease activity of the full-length NS3-NS4a and the protease domain were measured using a FRET-based assay using a peptide substrate derived fr...More data for this Ligand-Target Pair