Compile Data Set for Download or QSAR
Found 60 of ic50 for UniProtKB: P31749
LigandPNGBDBM431867(US10550114, Compound 1a)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028WJ8PubMed
LigandPNGBDBM182517(US9145392, 218)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM50550738(CHEMBL4792262)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human AKT assessed as inhibition of substrate phosphorylation using AKTide-2T as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FXBPubMed
LigandPNGBDBM50572156(CHEMBL4853207)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM50550740(CHEMBL4780030)copy SMILES
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human AKT assessed as inhibition of substrate phosphorylation using AKTide-2T as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FXBPubMed
LigandPNGBDBM182373(US9145392, 74)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182529(US9145392, 230)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182519(US9145392, 220)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182390(US9145392, 91)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM50593633(ARQ 092 | ARQ 092 FREE BASE | ARQ-092 | Arq-092 | ...)copy SMILES
LigandPNGBDBM182413(US9145392, 114)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182307(US9145392, 8)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM50572155(CHEMBL4876889)copy SMILES
Affinity DataIC50: 7.30nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM50550739(CHEMBL4788683)copy SMILES
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human AKT assessed as inhibition of substrate phosphorylation using AKTide-2T as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FXBPubMed
LigandPNGBDBM182372(US9145392, 73)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182381(US9145392, 82)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182377(US9145392, 78)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM50528415(CHEMBL4457064)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of Akt in human LNCaP cells assessed as reduction in PRAS40 phosphorylation at T246 residue after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4P7WPubMed
LigandPNGBDBM182518(US9145392, 219)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM50528416(CHEMBL4440965)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of Akt in human LNCaP cells assessed as reduction in PRAS40 phosphorylation at T246 residue after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4P7WPubMed
LigandPNGBDBM182337(US9145392, 38)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182356(US9145392, 57)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182367(US9145392, 68)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182306(US9145392, 7)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182361(US9145392, 62)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM224325(US10080750, Compound 2 | US9321760, 2 | US9662330,...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182308(US9145392, 9)copy SMILEScopy InChI
Affinity DataIC50: 518nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182354(US9145392, 55)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182347(US9145392, 48)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182338(US9145392, 39)copy SMILEScopy InChI
Affinity DataIC50: 930nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182311(US9145392, 12)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM224350(US10080750, Compound 27 | US9321760, 27 | US966233...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM224477(US10080750, Compound 155 | US9321760, 155 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM224481(US10080750, Compound 159 | US9321760, 159 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM224329(US10080750, Compound 6 | US9321760, 6 | US9662330,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM50095232(6-Methoxy-7-(3-morpholin-4-yl-propoxy)-4-(4-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Akt phosphorylation in LoVo cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P84B8TPubMed
LigandPNGBDBM28123(3-cyanoquinoline, 8 | 4-({3-chloro-4-[(1-methyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MEK1 phosphorylation in LoVo cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P84B8TPubMed
LigandPNGBDBM224338(US10080750, Compound 15 | US9321760, 15 | US966233...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182321(US9145392, 22)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182322(US9145392, 23)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM50451248(CHEMBL2368948)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Akt (proto-oncogenic serine/threonine) kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765DMSPubMed
LigandPNGBDBM50451248(CHEMBL2368948)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Akt (proto-oncogenic serine/threonine PKB) kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BTDPubMed
LigandPNGBDBM50204693(3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of AKT by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5V22PubMed
LigandPNGBDBM182336(US9145392, 37)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM182309(US9145392, 10)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49H5PubMed
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human AKT assessed as inhibition of substrate phosphorylation using AKTide-2T as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FXBPubMed
LigandPNGBDBM50204694(3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL...)copy SMILEScopy InChI
Affinity DataIC50: 4.43E+3nMAssay Description:Inhibition of AKT by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5V22PubMed
LigandPNGBDBM50472751(CHEMBL2367874)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Akt (proto-oncogenic serine/threonine PKB) kinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BTDPubMed
LigandPNGBDBM50189603(CHEMBL377734 | N-cyclopropyl-2,4-difluoro-5-((2-(p...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1RBMPubMed
LigandPNGBDBM50091042(CHEMBL2368953 | Carbonic acid (R)-2-methoxy-3-octa...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Akt (proto-oncogenic serine/threonine) kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765DMSPubMed
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