Compile Data Set for Download or QSAR
Found 25 of ic50 for UniProtKB: P22002
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM81939(CAS_52-53-9 | NSC_62969 | VERAPAMIL)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 60 mM K+-induced contractionMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM81939(CAS_52-53-9 | NSC_62969 | VERAPAMIL)copy SMILEScopy InChI
Affinity DataIC50: 398nMAssay Description:Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of phenylephrine-induced contractionMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM81939(CAS_52-53-9 | NSC_62969 | VERAPAMIL)copy SMILEScopy InChI
Affinity DataIC50: 481nMAssay Description:Inhibition of L-type calcium channel in Wistar rat aorta rings assessed as reduction in L-type Ba(2+) current at Vh of -50 mVMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50280989(2,6-dimethyl-5-methyloxycarbonyl-4-(3-nitrophenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 592nMAssay Description:Inhibition of [3H]PN-200-110 binding to L-type calcium channels in rat cortex membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JS8
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50080302(2-(1-azepanylmethyl)-4-{1-[3-(1-azepanylmethyl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of L-type calcium channels in GH-3 rat pituitary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB524MPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM81939(CAS_52-53-9 | NSC_62969 | VERAPAMIL)copy SMILEScopy InChI
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of L-type calcium channel in endothelium-intact Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contractionMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50080296(2-(1-azepanylmethyl)-4-{1-[3-(1-azepanylmethyl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of L-type calcium channels in GH-3 rat pituitary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB524MPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50085561(4-[2-(3-{2-[2-(3-Hydroxy-phenyl)-ethyl]-benzyloxy}...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of L-type [Ca2+] channel (VSCC) in rat A7r5 vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JKZPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50080295(2-(1-azepanylmethyl)-4-{1-[3-(1-azepanylmethyl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of L-type calcium channels in GH-3 rat pituitary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB524MPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50085560(4-[2-(3-{2-[2-(4-Hydroxy-phenyl)-ethyl]-benzyloxy}...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of L-type [Ca2+] channel (VSCC) in rat A7r5 vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JKZPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50212319(CHEMBL18412)copy SMILEScopy InChI
Affinity DataIC50: 5.87E+3nMAssay Description:Displacement of [3H]nitrendipine from calcium channel receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47RB8
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50080299(2-(1-azepanylmethyl)-4-{1-[3-(1-azepanylmethyl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of L-type calcium channels in GH-3 rat pituitary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB524MPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50019968(7-Ethyl-1,3,5-trimethyl-6,7-dihydro-1H-1,2,4,5a,8-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nitrendipine from L-type [Ca2+] channel of rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JGGPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50046397(CHEMBL3314412)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 60 mM K+-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4K1NPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50046397(CHEMBL3314412)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of phenylephrine-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4K1NPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50046397(CHEMBL3314412)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4K1NPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50046397(CHEMBL3314412)copy SMILEScopy InChI
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of L-type calcium channel in endothelium-intact Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4K1NPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50046399(CHEMBL3314413)copy SMILEScopy InChI
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of phenylephrine-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4K1NPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50046399(CHEMBL3314413)copy SMILEScopy InChI
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of L-type calcium channel in endothelium-intact Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4K1NPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50046399(CHEMBL3314413)copy SMILEScopy InChI
Affinity DataIC50: 7.94E+4nMAssay Description:Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 60 mM K+-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4K1NPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50046399(CHEMBL3314413)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4K1NPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50046397(CHEMBL3314412)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+5nMAssay Description:Inhibition of L-type calcium channel in Wistar rat aorta rings assessed as reduction in L-type Ba(2+) current at Vh of -50 mVMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4K1NPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50230150(CHEMBL345052)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+6nMAssay Description:Calcium channel binding activity against dihydropyridine receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4MQBPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50001689(4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+6nMAssay Description:Calcium channel binding activity against dihydropyridine receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4MQBPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Vietnam Academy of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50230151(CHEMBL136313)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+6nMAssay Description:Calcium channel binding activity against dihydropyridine receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4MQBPubMed