Compile Data Set for Download or QSAR
Found 66 of ic50 for UniProtKB: P32300
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 0.360nMAssay Description:Compound was tested for antagonistic activity against opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1FW0PubMed
LigandPNGBDBM50369571(CHEMBL1790710)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Opioid receptor activity was evaluated using mouse vas deferens (MVD) assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ11Q1PubMed
LigandPNGBDBM50001683(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deference.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RTZPubMed
LigandPNGBDBM50225846(CHEMBL293145)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Compound was tested for agonist activity against opioid receptor in mouse vas deferens preparationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50Q50PubMed
LigandPNGBDBM50002184(CHEMBL415330 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-A...)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB51XHPubMed
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 8.40nMAssay Description:Concentration required to inhibit the specific binding of tritiated ligand [3H]DADL to opiate receptor by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DB842CPubMed
LigandPNGBDBM21025((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Concentration required to inhibit the specific binding of tritiated ligand [3H]DADL to opiate receptor by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DB842CPubMed
LigandPNGBDBM50225254(CHEMBL610531)copy SMILEScopy InChI
Affinity DataIC50: 12.5nMAssay Description:In vitro binding affinity against opioid receptor using 1 nM [3H]- Naltrexone in the presence of 100 mM NaCl.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J105CXPubMed
LigandPNGBDBM50225254(CHEMBL610531)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:In vitro binding affinity against opioid receptor using 1 nM [3H]- Naltrexone in the presence of 100 mM NaCl.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J105CXPubMed
LigandPNGBDBM50225849(CHEMBL301654)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Compound was tested for agonist activity against opioid receptor in mouse vas deferens preparationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50Q50PubMed
LigandPNGBDBM50225254(CHEMBL610531)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:In vitro binding affinity against opioid receptor using 1 nM of [3H]- Naltrexone in the absence of NaClMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J105CXPubMed
LigandPNGBDBM50225254(CHEMBL610531)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:In vitro binding affinity against opioid receptor using 1 nM of [3H]- Naltrexone in the absence of NaClMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J105CXPubMed
LigandPNGBDBM50010701(CHEMBL410616 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D-Cys...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB51XHPubMed
LigandPNGBDBM50010703(CHEMBL443068 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Cys-A...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB51XHPubMed
LigandPNGBDBM50225847(CHEMBL54820)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Compound was tested for agonist activity against opioid receptor in mouse vas deferens preparationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50Q50PubMed
LigandPNGBDBM50010702(CHEMBL411557 | DYNORPHIN(1-17)-OH | Dynorphin A (1...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB51XHPubMed
LigandPNGBDBM50010706(CHEMBL384250 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D-Cys...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB51XHPubMed
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Concentration required to inhibit [3H]naltrexone binding to Opioid receptorsMore data for this Ligand-Target Pair
LigandPNGBDBM50231235(CHEMBL441636)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CZ367FPubMed
LigandPNGBDBM50231227(CHEMBL328583)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CZ367FPubMed
LigandPNGBDBM50367061(NALORPHINE | NALORPHINE HYDROCHLORIDE)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Concentration required to inhibit the stereospecific [3H]diprenorphine binding Opioid receptors in the absence of sodium(Na+) was determined in mouse...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X2C4KPubMed
LigandPNGBDBM50225845(CHEMBL293967)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Compound was tested for agonist activity against opioid receptor in mouse vas deferens preparationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50Q50PubMed
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Concentration required to inhibit the specific binding of tritiated ligand [3H]-naloxone to opiate receptor by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DB842CPubMed
LigandPNGBDBM50247803(Beta-Funeltrexamine | CHEMBL473136 | beta-funaltre...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Compound was tested for agonist activity against opioid receptor in mouse vas deferens preparationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50Q50PubMed
LigandPNGBDBM50001674(14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deferenceMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RTZPubMed
LigandPNGBDBM50225255(CHEMBL2310924)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:In vitro binding affinity against opioid receptor using 1 nM of [3H]- Naltrexone in the absence of NaClMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J105CXPubMed
LigandPNGBDBM50225255(CHEMBL2310924)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:In vitro binding affinity against opioid receptor using 1 nM of [3H]- Naltrexone in the absence of NaClMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J105CXPubMed
LigandPNGBDBM50001675(14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04...)copy SMILEScopy InChI
Affinity DataIC50: 124nMAssay Description:Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deferenceMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RTZPubMed
LigandPNGBDBM50231230(CHEMBL328019)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CZ367FPubMed
LigandPNGBDBM50367061(NALORPHINE | NALORPHINE HYDROCHLORIDE)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Concentration required to inhibit the stereospecific [3H]diprenorphine binding Opioid receptors in the presence of sodium(Na+) was determined in mous...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X2C4KPubMed
LigandPNGBDBM50001679(22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0...)copy SMILEScopy InChI
Affinity DataIC50: 171nMAssay Description:Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deferenceMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RTZPubMed
LigandPNGBDBM50001677(22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0...)copy SMILEScopy InChI
Affinity DataIC50: 179nMAssay Description:Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deferenceMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RTZPubMed
LigandPNGBDBM50231233(CHEMBL92960)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CZ367FPubMed
LigandPNGBDBM50010704(CHEMBL216640 | Dyn A(1-11)-NH2 | Dynorphin A analo...)copy SMILEScopy InChI
Affinity DataIC50: 204nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB51XHPubMed
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)copy SMILEScopy InChI
Affinity DataIC50: 258nMAssay Description:Opioid receptor activity was evaluated using mouse vas deferens (MVD) assayMore data for this Ligand-Target Pair
LigandPNGBDBM50231240(CHEMBL92779)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CZ367FPubMed
LigandPNGBDBM50010705(CHEMBL385759 | H-Tyr-Gly-Gly-Phe-Cys-Arg-Arg-Ile-A...)copy SMILEScopy InChI
Affinity DataIC50: 421nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB51XHPubMed
LigandPNGBDBM50026752(1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CZ367FPubMed
LigandPNGBDBM50225255(CHEMBL2310924)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:In vitro binding affinity against opioid receptor using 1 nM [3H]- Naltrexone in the presence of 100 mM NaCl.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J105CXPubMed
LigandPNGBDBM50225255(CHEMBL2310924)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:In vitro binding affinity against opioid receptor using 1 nM [3H]- Naltrexone in the presence of 100 mM NaCl.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J105CXPubMed
LigandPNGBDBM50231231(CHEMBL92124)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CZ367FPubMed
LigandPNGBDBM50010700(CHEMBL265824 | H-Tyr-Gly-Gly-Phe-Cys-Arg-Arg-D-Ala...)copy SMILEScopy InChI
Affinity DataIC50: 1.66E+3nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue mouse vas deferens (MVD)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB51XHPubMed
LigandPNGBDBM50003560(4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.0...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Concentration required to inhibit [3H]naltrexone binding to Opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P33VWPubMed
LigandPNGBDBM50223879(CHEMBL280688)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Concentration required to inhibit [3H]naltrexone binding to Opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P33VWPubMed
LigandPNGBDBM50231236(CHEMBL89961)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CZ367FPubMed
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Concentration required to inhibit [3H]naltrexone binding to Opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P33VWPubMed
LigandPNGBDBM50231241(CHEMBL285244)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CZ367FPubMed
LigandPNGBDBM50231237(CHEBI:6125 | Cetobemidone | Cliradon | Cymidon | K...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Tested for displacement of radioligand [3H]-Naloxone from opiate receptor; value ranges from 7-10 uMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CZ367FPubMed
LigandPNGBDBM50231228(CHEMBL96626)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate (experi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CZ367FPubMed
LigandPNGBDBM50223880(CHEMBL610906)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+3nMAssay Description:Concentration required to inhibit the stereospecific [3H]diprenorphine binding Opioid receptors in the absence of sodium(Na+) was determined in mouse...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X2C4KPubMed
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