Compile Data Set for Download or QSAR
Found 4 of ic50 for UniProtKB: P08684
TargetCytochrome P450 3A4/3A43/3A5/3A7(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50464556(CHEMBL4289811 | US10464907, Compound 21f | US10889...)copy SMILEScopy InChI
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibition of CYP3A in human pooled human liver microsomes using midazolam as substrate assessed as midazolam 1'-hydroxylation preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C713MPubMed
TargetCytochrome P450 3A4/3A43/3A5/3A7(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50508419(CHEMBL4471264)copy SMILEScopy InChI
Affinity DataIC50: 3.66E+4nMAssay Description:Inhibition of CYP3A in human liver microsomes assessed as reduction in midazolam 1'-hydroxylation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2F8HPubMed
TargetCytochrome P450 3A4/3A43/3A5/3A7(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50527104(CHEMBL4447583)copy SMILEScopy InChI
Affinity DataIC50: 6.22E+4nMAssay Description:Inhibition of CYP3A in human liver microsomes using testosterone as substrate preincubated for 5 mins followed by NADPH addition and measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RC7PubMed
TargetCytochrome P450 3A4/3A43/3A5/3A7(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50527104(CHEMBL4447583)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A in human liver microsomes using midazolam as substrate preincubated for 5 mins followed by NADPH addition and measured for 10 to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63RC7PubMed