Compile Data Set for Download or QSAR
Found 20 of ic50 for UniProtKB: P42261
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459036(CHEMBL4211865)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459020(CHEMBL4203681)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459021(CHEMBL4212408 | US10611730, Example 76)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459031(CHEMBL4216837)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459028(CHEMBL4216045 | US10611730, Example 160)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459032(CHEMBL4215352)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459030(CHEMBL4207238 | US10611730, Example 124)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459026(CHEMBL4214902 | US10611730, Example 31)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459019(CHEMBL4207505)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459022(CHEMBL4214549 | US10611730, Example 49)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459033(CHEMBL4211080 | US10611730, Example 36)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50509854(CHEMBL4439385)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Negative allosteric modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293 cells assessed as inhibition of glutamate-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4MRGPubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459035(CHEMBL4207659 | US10611730, Example 20)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459025(CHEMBL4211593 | US10611730, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50509858(CHEMBL4526929)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Negative allosteric modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293 cells assessed as inhibition of glutamate-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4MRGPubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459023(CHEMBL4202885 | US10611730, Example 69)copy SMILEScopy InChI
Affinity DataIC50: 251nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459029(CHEMBL4218962 | US10611730, Example 56)copy SMILEScopy InChI
Affinity DataIC50: 251nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459034(CHEMBL4206704)copy SMILEScopy InChI
Affinity DataIC50: 398nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459024(CHEMBL4212562)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+3nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed
TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Research & Development L.L.C.

Curated by ChEMBL
LigandPNGBDBM50459027(CHEMBL4214773)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+3nMAssay Description:Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3PubMed