Compile Data Set for Download or QSAR
Found 111 of ic50 for UniProtKB: P09211
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257496(US9493441, 14-1)copy SMILEScopy InChI
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257495(US9493441, 19-1)copy SMILEScopy InChI
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257449(US9493441, 4-33)copy SMILEScopy InChI
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257448(US9493441, 4-32)copy SMILEScopy InChI
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257457(US9493441, 6-3)copy SMILEScopy InChI
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257460(US9493441, 8)copy SMILEScopy InChI
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257458(US9493441, 6-4)copy SMILEScopy InChI
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257454(US9493441, 5)copy SMILEScopy InChI
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257451(US9493441, 4-35)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257447(US9493441, 4-31)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257445(US9493441, 4-29)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257429(BDBM257439 | US9493441, 4-13)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257435(US9493441, 4-19)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257429(BDBM257439 | US9493441, 4-13)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257418(US9493441, 4-2)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257450(US9493441, 4-34)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257494(US9493441, 18-1)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257492(US9493441, 17-4)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257459(US9493441, 7)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257417(US9493441, 4-1)copy SMILEScopy InChI
Affinity DataIC50: 3nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257438(US9493441, 4-22)copy SMILEScopy InChI
Affinity DataIC50: 3nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257424(US9493441, 4-8)copy SMILEScopy InChI
Affinity DataIC50: 5nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257483(US9493441, 14-2)copy SMILEScopy InChI
Affinity DataIC50: 5nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257416(US9493441, 3-3)copy SMILEScopy InChI
Affinity DataIC50: 5nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257430(US9493441, 4-14)copy SMILEScopy InChI
Affinity DataIC50: 5nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257453(US9493441, 4-37)copy SMILEScopy InChI
Affinity DataIC50: 5nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257452(US9493441, 4-36)copy SMILEScopy InChI
Affinity DataIC50: 5nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257425(US9493441, 4-9)copy SMILEScopy InChI
Affinity DataIC50: 6nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257500(US9493441, 19-2)copy SMILEScopy InChI
Affinity DataIC50: 6nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257469(US9493441, 11-7)copy SMILEScopy InChI
Affinity DataIC50: 7nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257391(BDBM257486 | US9493441, 1-2)copy SMILEScopy InChI
Affinity DataIC50: 7nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257428(US9493441, 4-12)copy SMILEScopy InChI
Affinity DataIC50: 7nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257462(US9493441, 10)copy SMILEScopy InChI
Affinity DataIC50: 7nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257437(US9493441, 4-21)copy SMILEScopy InChI
Affinity DataIC50: 8nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257394(US9493441, 1-5)copy SMILEScopy InChI
Affinity DataIC50: 9nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257427(US9493441, 4-11)copy SMILEScopy InChI
Affinity DataIC50: 9nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257431(US9493441, 4-15)copy SMILEScopy InChI
Affinity DataIC50: 9nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257390(US9493441, 1-1)copy SMILEScopy InChI
Affinity DataIC50: 10nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257491(US9493441, 17-3)copy SMILEScopy InChI
Affinity DataIC50: 10nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257444(US9493441, 4-28)copy SMILEScopy InChI
Affinity DataIC50: 11nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257410(US9493441, 1-21)copy SMILEScopy InChI
Affinity DataIC50: 12nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257419(US9493441, 4-3)copy SMILEScopy InChI
Affinity DataIC50: 12nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257426(US9493441, 4-10)copy SMILEScopy InChI
Affinity DataIC50: 12nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257423(US9493441, 4-7)copy SMILEScopy InChI
Affinity DataIC50: 13nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257391(BDBM257486 | US9493441, 1-2)copy SMILEScopy InChI
Affinity DataIC50: 13nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257433(US9493441, 4-17)copy SMILEScopy InChI
Affinity DataIC50: 13nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257446(US9493441, 4-30)copy SMILEScopy InChI
Affinity DataIC50: 15nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257493(US9493441, 17-5)copy SMILEScopy InChI
Affinity DataIC50: 16nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257405(US9493441, 1-16)copy SMILEScopy InChI
Affinity DataIC50: 19nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM257406(US9493441, 1-17)copy SMILEScopy InChI
Affinity DataIC50: 19nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J69S2US Patent
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