Compile Data Set for Download or QSAR
Found 147 of ic50 for UniProtKB: P30543
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004566(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinaz...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7WKFPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004566(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinaz...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50023492(5-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009535((CGS 22,989) 2-[6-Amino-2-(2-cyclohex-1-enyl-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009543(2-{6-Amino-2-[2-(5,6,7,8-tetrahydro-naphthalen-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50023505(2-Furan-2-yl-9-methoxy-[1,2,4]triazolo[1,5-c]quina...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50004571(8-Chloro-1-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7WKFPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009509((CGS 22,492) 2-[6-Amino-2-(2-cyclohexyl-ethylamino...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50015779(7,8-Dichloro-1-ethyl-[1,2,4]triazolo[4,3-a]quinoxa...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7WKFPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009546(2-{6-Amino-2-[2-(4-methoxy-phenyl)-ethylamino]-pur...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009515(2-[6-Amino-2-(2-hydroxy-2-phenyl-propylamino)-puri...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]-NECA from adenosine A2 receptor of rat striatal membraneMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009513(2-[2-(2-Adamantan-1-yl-ethylamino)-6-amino-purin-9...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50023496(2-Furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50015765(8-Chloro-1-ethyl-[1,2,4]triazolo[4,3-a]quinoxalin-...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7WKFPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50015810(7-Chloro-1-ethyl-[1,2,4]triazolo[4,3-a]quinoxalin-...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7WKFPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50453087(CHEMBL2374394)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50015829(8-Chloro-1-(4-chloro-phenyl)-[1,2,4]triazolo[4,3-a...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7WKFPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009541(2-[6-Amino-2-(2-naphthalen-2-yl-ethylamino)-purin-...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50015784(1-Ethyl-7-methoxy-[1,2,4]triazolo[4,3-a]quinoxalin...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7WKFPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009527(2-[6-Amino-2-(2-bicyclo[2.2.1]hept-2-yl-ethylamino...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50453086(CHEMBL2374393)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009519(3-(4-{2-[6-Amino-9-(3,4-dihydroxy-5-hydroxymethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50015798(8-Chloro-1-trifluoromethyl-[1,2,4]triazolo[4,3-a]q...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7WKFPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009511(4-{2-[6-Amino-9-(3,4-dihydroxy-5-hydroxymethyl-tet...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009545(2-{6-Amino-2-[2-(1H-indol-3-yl)-ethylamino]-purin-...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50023495(2-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]qui...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50023499((9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quina...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009516((4-{2-[6-Amino-9-(3,4-dihydroxy-5-hydroxymethyl-te...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50015771(1-Ethyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-ylamine...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7WKFPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009508(2-{6-Amino-2-[2-(4-bromo-thiophen-2-yl)-ethylamino...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009531(2-[6-Amino-2-(2-phenyl-propylamino)-purin-9-yl]-5-...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009530(3-(4-{2-[6-Amino-9-(3,4-dihydroxy-5-hydroxymethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009548(2-[6-Amino-2-(4-phenyl-butylamino)-purin-9-yl]-5-h...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50453083(CHEMBL2374398)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50453082(CHEMBL2374416)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50453085(CHEMBL2374396)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50015788(7-Methoxy-[1,2,4]triazolo[4,3-a]quinoxalin-4-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7WKFPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50015748(8-Fluoro-1-trifluoromethyl-[1,2,4]triazolo[4,3-a]q...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7WKFPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009528(CHEMBL2374415 | [2-(4-{2-[6-Amino-9-(3,4-dihydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 112nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50023503(9-Chloro-2-thiophen-2-yl-[1,2,4]triazolo[1,5-c]qui...)copy SMILEScopy InChI
Affinity DataIC50: 116nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009529(2-(6-Amino-2-{2-[4-(2-cyclohexyl-ethyl)-phenyl]-et...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50453081(CHEMBL2374397)copy SMILEScopy InChI
Affinity DataIC50: 132nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009540((3-{2-[6-Amino-9-(3,4-dihydroxy-5-hydroxymethyl-te...)copy SMILEScopy InChI
Affinity DataIC50: 132nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009542(2-[6-Amino-2-(4-cyclohexyl-butylamino)-purin-9-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 138nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50023506(9-Chloro-2-furan-3-yl-[1,2,4]triazolo[1,5-c]quinaz...)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43S4WPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50009520(2-[6-Amino-2-(methyl-phenethyl-amino)-purin-9-yl]-...)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM82022(2-(Phenylamino)ado (CV-1808) | 2-[6-Amino-2-(3-cyc...)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66NNPubMed
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