Compile Data Set for Download or QSAR
Found 31 of ic50 for UniProtKB: P25024
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50475205(CHEMBL190899)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89G5HPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50169045((R)-2-(4-isobutylphenyl)-N-(methylsulfonyl)propana...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89G5HPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50169048((R)-2-(3-Benzoyl-phenyl)-propionic acid | (R)-2-(3...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89G5HPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50113628(CHEMBL431511 | [5-(4-Fluoro-phenylcarbamoyl)-pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219799(CHEMBL36535)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219797(CHEMBL36934)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50088570((S)-2-(3-Benzoyl-phenyl)-propionic acid | (S)-2-(3...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89G5HPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219796(CHEMBL39464)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50475204(CHEMBL192943)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89G5HPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219800(CHEMBL432475)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219806(CHEMBL291140)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50169047((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89G5HPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219809(CHEMBL36643)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50169044((-)-ibuprofen | (2R)-2-(4-isobutylphenyl)propanoic...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89G5HPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219811(CHEMBL39710)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219812(CHEMBL36842)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219794(CHEMBL289656)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219808(CHEMBL288527)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219810(CHEMBL288876)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219795(CHEMBL40080)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219789(CHEMBL40955)copy SMILEScopy InChI
Affinity DataIC50: 680nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219793(CHEMBL289789)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219790(CHEMBL39937)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219801(CHEMBL40558)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219798(CHEMBL39988)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219792(CHEMBL40114)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50213962(CHEMBL410765)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Compound was tested for inhibitory activity against Interleukin-8 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P55QP3
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219788(CHEMBL36797)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219791(CHEMBL35938)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50219807(CHEMBL288457)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£ S.p.A.

Curated by ChEMBL
LigandPNGBDBM50113636(CHEMBL39835 | [5-(4-Fluoro-phenylcarbamoyl)-pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28ZDPubMed