Compile Data Set for Download or QSAR
Found 12 of ic50 for UniProtKB: P08700
TargetEpidermal growth factor receptor/Interleukin-3(Homo sapiens (Human))TBA
LigandPNGBDBM547888(WO2022090481, Example I-107)copy SMILES
Affinity DataIC50: 633nMAssay Description: This assay quantifies the phosphorylation of EGFR at Tyr1068 and was used to measure the inhibitory effect of compounds on the transgenic EGFR del19...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765JH3PubMed
TargetEpidermal growth factor receptor/Interleukin-3(Homo sapiens (Human))TBA
LigandPNGBDBM547983(WO2022090481, Example I-204)copy SMILES
Affinity DataIC50: 816nMAssay Description: This assay quantifies the phosphorylation of EGFR at Tyr1068 and was used to measure the inhibitory effect of compounds on the transgenic EGFR del19...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765JH3PubMed
TargetEpidermal growth factor receptor/Interleukin-3(Homo sapiens (Human))TBA
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description: This assay quantifies the phosphorylation of EGFR at Tyr1068 and was used to measure the inhibitory effect of compounds on the transgenic EGFR del19...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor/Interleukin-3(Homo sapiens (Human))TBA
LigandPNGBDBM112499(DACOMITINIB | US8623883, No. 2 | WO2022090481, Exa...)copy SMILEScopy InChI
Affinity DataIC50: 978nMAssay Description: This assay quantifies the phosphorylation of EGFR at Tyr1068 and was used to measure the inhibitory effect of compounds on the transgenic EGFR del19...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor/Interleukin-3(Homo sapiens (Human))TBA
LigandPNGBDBM50322823((S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahy...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+3nMAssay Description: This assay quantifies the phosphorylation of EGFR at Tyr1068 and was used to measure the inhibitory effect of compounds on the transgenic EGFR del19...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor/Interleukin-3(Homo sapiens (Human))TBA
LigandPNGBDBM547941(WO2022090481, Example I-162)copy SMILES
Affinity DataIC50: 1.37E+3nMAssay Description: This assay quantifies the phosphorylation of EGFR at Tyr1068 and was used to measure the inhibitory effect of compounds on the transgenic EGFR del19...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765JH3PubMed
TargetEpidermal growth factor receptor/Interleukin-3(Homo sapiens (Human))TBA
LigandPNGBDBM547965(WO2022090481, Example I-186)copy SMILES
Affinity DataIC50: 1.63E+3nMAssay Description: This assay quantifies the phosphorylation of EGFR at Tyr1068 and was used to measure the inhibitory effect of compounds on the transgenic EGFR del19...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765JH3PubMed
TargetEpidermal growth factor receptor/Interleukin-3(Homo sapiens (Human))TBA
LigandPNGBDBM547807(WO2022090481, Example I-022 | WO2022090481, Exampl...)copy SMILES
Affinity DataIC50: 2.94E+3nMAssay Description: This assay quantifies the phosphorylation of EGFR at Tyr1068 and was used to measure the inhibitory effect of compounds on the transgenic EGFR del19...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765JH3PubMed
TargetEpidermal growth factor receptor/Interleukin-3(Homo sapiens (Human))TBA
LigandPNGBDBM547940(WO2022090481, Example I-161)copy SMILES
Affinity DataIC50: 3.80E+3nMAssay Description: This assay quantifies the phosphorylation of EGFR at Tyr1068 and was used to measure the inhibitory effect of compounds on the transgenic EGFR del19...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765JH3PubMed
TargetEpidermal growth factor receptor/Interleukin-3(Homo sapiens (Human))TBA
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description: This assay quantifies the phosphorylation of EGFR at Tyr1068 and was used to measure the inhibitory effect of compounds on the transgenic EGFR del19...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor/Interleukin-3(Homo sapiens (Human))TBA
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description: This assay quantifies the phosphorylation of EGFR at Tyr1068 and was used to measure the inhibitory effect of compounds on the transgenic EGFR del19...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor/Interleukin-3(Homo sapiens (Human))TBA
LigandPNGBDBM50160870(CHEMBL3787344 | US11896597, Compound EGF816 | WO20...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description: This assay quantifies the phosphorylation of EGFR at Tyr1068 and was used to measure the inhibitory effect of compounds on the transgenic EGFR del19...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765JH3PubMed