Compile Data Set for Download or QSAR
Found 9 of ic50 for UniProtKB: P03366
TargetGag-Pol polyprotein [600-1027,V705A]/[600-1155,V705A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM2014(2-ethyl-5-(1H-indol-3-yl)-9-methyl-2,4,9,15-tetraa...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26W9KPubMed
TargetGag-Pol polyprotein [600-1027,V705A]/[600-1155,V705A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM2104(13-[2-(3-aminophenyl)ethyl]-5-chloro-2-ethyl-9-met...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3BH2PubMed
TargetGag-Pol polyprotein [600-1027,V705A]/[600-1155,V705A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM2113(13-[2-(2-aminopyridin-4-yl)ethyl]-5-chloro-2-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3BH2PubMed
TargetGag-Pol polyprotein [600-1027,V705A]/[600-1155,V705A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM2019(2-(6-Azaindol-3-yl)-5,11-dihydro-11-ethyl-5-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 228nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26W9KPubMed
TargetGag-Pol polyprotein [600-1027,V705A]/[600-1155,V705A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM2096(2,8-Substituted Dipyridodiazepinone 39 | 2-ethyl-5...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3BH2PubMed
TargetGag-Pol polyprotein [600-1027,V705A]/[600-1155,V705A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM2021(2,8-Disubstituted Dipyridodiazepinone 37 | 2,8-Sub...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3BH2PubMed
TargetGag-Pol polyprotein [600-1027,V705A]/[600-1155,V705A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM2022(2,8-Disubstituted Dipyridodiazepinone 36 | 2,8-Sub...)copy SMILEScopy InChI
Affinity DataIC50: 840nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3BH2PubMed
TargetGag-Pol polyprotein [600-1027,V705A]/[600-1155,V705A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM1553(2-ethyl-9-methyl-5-(1H-pyrrol-3-yl)-2,4,9,15-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26W9KPubMed
TargetGag-Pol polyprotein [600-1027,V705A]/[600-1155,V705A](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM2015(2-ethyl-5-(5-methoxy-1H-indol-3-yl)-9-methyl-2,4,9...)copy SMILEScopy InChI
Affinity DataIC50: 3.09E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26W9KPubMed