Compile Data Set for Download or QSAR
Found 22 of ic50 for UniProtKB: P21709
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of EphA1 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ663GPubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50204290(CHEMBL3979920 | US11077111, Compound IIIa | US2023...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant GST-tagged EPHA1 cytoplasmic domain (568 to 976 residues) expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29888Z2PubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of EPHA1 (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PQTPubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50330905(7-(2,6-difluoro-4-((1S,4S)-5-methyl-2,5-diazabicyc...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of EPHA1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58Q3PubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 95.3nMAssay Description:Inhibition of human EPHA1 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5KB8PubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 139nMAssay Description:Inhibition of human EPHA1 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W380MTPubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 143nMAssay Description:Binding affinity to human EPHA1 using poly[Glu:Tyr] (4:1) as substrate by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1J37PubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)copy SMILES
Affinity DataIC50: 292nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J96BC1PubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50584948(CHEMBL5092606)copy SMILES
Affinity DataIC50: 303nMAssay Description:Inhibition of human recombinant EPHA1 incubated for 1 hrs by HTRF KinEASE TK assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9W1FPubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50584949(CHEMBL5089164)copy SMILES
Affinity DataIC50: 393nMAssay Description:Inhibition of human recombinant EPHA1 incubated for 1 hrs by HTRF KinEASE TK assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9W1FPubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Inhibition of EPHA1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC61NHPubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50358591(CHEMBL1923983)copy SMILEScopy InChI
Affinity DataIC50: 686nMAssay Description:Inhibition of EPHA1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z038KCPubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM236557(US9365572, 5)copy SMILEScopy InChI
Affinity DataIC50: 1.47E+3nMpH: 7.5 T: 2°CAssay Description:Agents: 1-fold kinase buffer without MnCl2: 50 mM HEPES, pH 7.5, 0.0015% Brij-35, 10 mM MgCl2, 2 mM DTT. 1-fold kinase buffer with MnCl2: 50 mM HEPES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4TNCUS Patent
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428059(CHEMBL2322989)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Displacement of ephrin-A1-Fc from EphA1 receptor Fc ectodomain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8G7HPubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50135286(CHEMBL3745885)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EPHA1 using poly[Glu:Tyr] (4:1) as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WT8PubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50509949(CHEMBL4475216 | US11667631, Example 29)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EphA1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB491WPubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human EphA1 (568 to end residues) using KKKSPGEYVNIEF as substrate after 40 mins in presence of [gamma-33ATP] by radiometri...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93FGPubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50556597(CHEMBL4756586)copy SMILES
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of C-terminal NanoLuc-fused full length EPHA1 (unknown origin) expressed in HEK293T cells after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5CGWPubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)copy SMILES
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from human EphA1 Fc preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELI...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X35233PubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50359359(CHEMBL1929238)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of EPHA1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC61NHPubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50182493(CHEMBL3818247 | US9512121, 22)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of EPHA1 (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PQTPubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of recombinant human GST-tagged EPHA1 cytoplasmic domain (568 to 976 residues) expressed in baculovirus expression system using Tyr 02 as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed