Compile Data Set for Download or QSAR
Found 11 of ic50 for UniProtKB: P16435
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236853(CHEMBL4094677)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibitory concentration required for antagonistic activity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24170BBPubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236859(CHEMBL4086536)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24170BBPubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM81348(β-Lapachone (A3) | Beta lapachone | R115 (Rea...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24170BBPubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236854(CHEMBL4074173)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibitory concentration required for antagonistic activity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24170BBPubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236863(CHEMBL3398294)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24170BBPubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236858(CHEMBL4098063)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Functional potency measured as intracellular calcium elevation in Hek-293 cells expressing hGHSR1aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24170BBPubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236857(CHEMBL4080037)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibitory concentration required for antagonistic activity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24170BBPubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236860(CHEMBL4065098)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Functional potency measured as intracellular calcium elevation in Hek-293 cells expressing hGHSR1aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24170BBPubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236861(CHEMBL3398292)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24170BBPubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236862(CHEMBL3398293)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+4nMAssay Description:Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24170BBPubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236855(CHEMBL4102425)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibitory concentration required for antagonistic activity at Metabotropic glutamate receptor 2; Maximum inhibition reached only 50%More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24170BBPubMed