Compile Data Set for Download or QSAR
Found 57 of ic50 for UniProtKB: P01112
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50092365((R)-1-((1H-imidazol-5-yl)methyl)-3-benzyl-4-(thiop...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44VBPPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50092365((R)-1-((1H-imidazol-5-yl)methyl)-3-benzyl-4-(thiop...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0M78PubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50089969(5-[Bis-(2-chloro-ethyl)-amino]-benzofuran-2-carbox...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J79PubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50089967(5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-1H...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J79PubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50089961(5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-1-...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J79PubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50089960(5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-1H...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J79PubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50089962(5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-be...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J79PubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50089971(5-[Bis-(2-chloro-ethyl)-amino]-1-methyl-1H-indole-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J79PubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50089978(5-[Bis-(2-chloro-ethyl)-amino]-1H-indole-2-carboxy...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J79PubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50060139(CHEMBL326352 | [(S)-1-((4-Benzyloxy-benzyl)-{[(1-p...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HQGPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50601400(CHEMBL5171806)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44VBPPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50601398(CHEMBL5174384)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44VBPPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50060141(CHEMBL431440 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-me...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HQGPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50060146(CHEMBL407445 | [(S)-1-((4-Benzyloxy-benzyl)-{[(1-p...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HQGPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50060140(CHEMBL115943 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-cy...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HQGPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50055659(2N-(3,3-aminoiminopropyl)-4-[4-(4-formamido-1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959J79PubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50060145(CHEMBL115669 | [(S)-1-{(4-Benzyloxy-benzyl)-[((S)-...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HQGPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50060138(CHEMBL324827 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-ph...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HQGPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50060142(CHEMBL326127 | [(S)-1-((4-Benzyloxy-benzyl)-{[(1-p...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HQGPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50060149(CHEMBL112512 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-ph...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HQGPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50060150(CHEMBL114281 | [(S)-1-{(4-Benzyloxy-benzyl)-[((R)-...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HQGPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50060144(CHEMBL325073 | [(S)-1-{(4-Benzyloxy-benzyl)-[((R)-...)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HQGPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50060148(CHEMBL325331 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HQGPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50060152(CHEMBL112879 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-et...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HQGPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287960(1-[(2R,6S)-6-(tert-Butyl-dimethyl-silanyloxymethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287951(3-[(3aS,4R,6R,6aR)-6-(4-Chloro-6-methoxy-3-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50478506(Ophirapstanol Trisulfate)copy SMILEScopy InChI
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of human recombinant p21RAS by GDPX assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q261133SPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287961((E)-5-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50059857(CHEMBL102955 | [(S)-1-[(4-Benzyloxy-benzyl)-(phene...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HQGPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287943((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287946(1-[(2R,6S)-6-(tert-Butyl-dimethyl-silanyloxymethyl...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50060143(CHEMBL324345 | [(S)-1-{(4-Benzyloxy-benzyl)-[((S)-...)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HQGPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287963(CHEMBL300769 | [(2S,6R)-6-(4-Chloro-6-methoxy-3-me...)copy SMILEScopy InChI
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287959((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287955((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50072339(Benzodiazepine-Distamycin Hybrid | CHEMBL102341)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Ha-ras polymerase-chain reaction productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GFMPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287958(CHEMBL303105 | [(2S,6R)-6-(4-Chloro-6-methoxy-3-me...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287944((E)-3-[(2S,3S,4R,5R)-5-(4-Chloro-6-methoxy-3-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287945(5-(4-chloro-6-methoxy-3-methyl-1H-pyrazolo[3,4-b]q...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287953(5-(4-chloro-6-methoxy-3-methyl-1H-pyrazolo[3,4-b]q...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287962(CHEMBL61870 | [(2S,6R)-4-Benzenesulfonyl-6-(4-chlo...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287949(1-[(2R,6S)-4-Benzenesulfonyl-6-(tert-butyl-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287948(CHEMBL64886 | [(2S,6R)-6-(4-Chloro-6-methoxy-3-met...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50059879(CHEMBL102492 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-be...)copy SMILEScopy InChI
Affinity DataIC50: 1.43E+4nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69HQGPubMed
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287956(Benzoic acid (3aR,4R,6R,6aR)-6-(4-chloro-6-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287947((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50610922(CHEMBL5209443)copy SMILES
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287952(CHEMBL304717 | N-{4-[(2S,6R)-2-(tert-Butyl-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50287954((E)-3-[(2S,5R)-5-(4-Chloro-6-methoxy-3-methyl-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G160TB
TargetGTPase HRas(Homo sapiens (Human))TBA
LigandPNGBDBM50601396(CHEMBL5197181)copy SMILES
Affinity DataIC50: 3.55E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44VBPPubMed
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