Compile Data Set for Download or QSAR
Found 56 of ic50 for UniProtKB: P56817
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16047((4S)-4-[(2S)-2-[(2R,4S,5S)-5-[(2S)-2-[(2S)-2-[(4S)...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16060((2R,3R)-3-[(1S,2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BPCPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16057((2S)-N-[(1S)-1-{[(1S,2S)-1-[(1R,2R)-2-{[(1S)-1-(bu...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16048((4S)-4-amino-4-{[(1S)-1-{[(1S)-2-carbamoyl-1-{[(1R...)copy SMILEScopy InChI
Affinity DataIC50: 12nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BPCPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16049((4S)-4-[(2S)-2-{[(1R,2R)-2-[(1S,2S)-2-[(2S)-2-[(2S...)copy SMILEScopy InChI
Affinity DataIC50: 16nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BPCPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16055((2S)-N-[(1S)-1-{[(1S,2S)-1-[(1R,2R)-2-{[(1S)-1-(bu...)copy SMILEScopy InChI
Affinity DataIC50: 25nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BPCPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16051((4S)-4-amino-4-{[(1S)-1-{[(1S)-2-carbamoyl-1-{[(1S...)copy SMILEScopy InChI
Affinity DataIC50: 39nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16050((2S)-2-[(2S)-2-{[(1R,2R)-2-[(1S,2S)-2-[(2S)-2-[(2S...)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BPCPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16078((2R,4S,5S)-N-butyl-5-[(2S)-2-[(2S)-2-acetamido-N,4...)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16077((2R,4S,5S)-N-butyl-5-[(2S)-2-[(2S)-2-acetamido-4-m...)copy SMILEScopy InChI
Affinity DataIC50: 120nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM29754(macrocyclic peptidomimetic, 3h)copy SMILEScopy InChI
Affinity DataIC50: 150nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NS3PubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16084(AXQ093 | tert-butyl N-[(3R,6S,9R,13E)-3-[(1S,3R)-3...)copy SMILEScopy InChI
Affinity DataIC50: 156nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16054((2S)-N-[(1S)-1-{[(1S,2S)-1-[(1R,2R)-2-{[(1S)-1-(bu...)copy SMILEScopy InChI
Affinity DataIC50: 185nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BPCPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16053((2S)-2-{[(1R,2R)-2-[(1S,2S)-2-[(2S)-2-[(2S)-2-acet...)copy SMILEScopy InChI
Affinity DataIC50: 190nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BPCPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16088((2R,4S)-4-[(4aS,12R,15S,17aS)-15-methyl-14,17-diox...)copy SMILEScopy InChI
Affinity DataIC50: 190nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM29750(macrocyclic peptidomimetic, 3d)copy SMILEScopy InChI
Affinity DataIC50: 250nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NS3PubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16081(Olefins were mixtures of cis and trans isomers. | ...)copy SMILEScopy InChI
Affinity DataIC50: 510nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM29748(NVP-ARV99 | macrocyclic peptidomimetic, 3b)copy SMILEScopy InChI
Affinity DataIC50: 590nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16052((2S)-2-{[(1R,2R)-2-[(1S,2S)-2-[(2S)-2-[(2S)-2-acet...)copy SMILEScopy InChI
Affinity DataIC50: 600nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BPCPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16062((2S)-2-{[(1R,2R)-2-[(1S,2S)-2-[(2S)-2-[(2S)-2-acet...)copy SMILEScopy InChI
Affinity DataIC50: 720nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BPCPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16082((2R,4S)-4-[(3S,6S,9R,13Z)-9-(acetylamino)-6-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+3nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16069(dithia macrocycle compound 28 | tert-butyl N-[(3R,...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM29744(hydroxyethylene tripeptide inhibitor, 1)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM29747(macrocyclic peptidomimetic, 3a)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NS3PubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16056((1R,2R)-N-butyl-2-[(1S,2S)-2-[(2S)-2-[(2S)-2-aceta...)copy SMILEScopy InChI
Affinity DataIC50: 1.82E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BPCPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16083(cis-dithia macrocycle compound 41 | tert-butyl N-[...)copy SMILEScopy InChI
Affinity DataIC50: 1.97E+3nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM29752(macrocyclic peptidomimetic, 3f)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NS3PubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM29746(N-methyl-alanine tripeptide inhibitor, 2b)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NS3PubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM29753(macrocyclic peptidomimetic, 3g)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NS3PubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16059((2S)-N-[(1S)-1-{[(1S,2S)-1-[(3S,4R)-4-{[(1S)-1-(bu...)copy SMILEScopy InChI
Affinity DataIC50: 3.35E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BPCPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16058((2S)-N-[(1S)-1-{[(1S,2S)-1-[(3S,4S)-4-{[(1S)-1-(bu...)copy SMILEScopy InChI
Affinity DataIC50: 3.44E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BPCPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM29745(hydroxyethylene tripeptide inhibitor, 2a)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NS3PubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM29749(macrocyclic peptidomimetic, 3c)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NS3PubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16068(dithia macrocycle compound 27 | tert-butyl N-[(3R,...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16061((2R,3S)-3-[(1S,2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4...)copy SMILEScopy InChI
Affinity DataIC50: 9.56E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BPCPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16070((2R,4S)-4-[(3R,6S,9R)-9-(acetylamino)-6-methyl-5,8...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16085((2R,4S)-4-[(8R,11S,13aR,17aS)-11-methyl-10,13-diox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16086((2R,4S)-4-[(8R,11S,13aS,17aR)-11-methyl-10,13-diox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16067(dithia macrocycle compound 26 | tert-butyl N-[(5R,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16089((2R,4S)-4-[(3S,6R,13aS,17aS)-3-methyl-1,4-dioxo-1H...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16090((2R,4S)-4-[(3S,6R,13aR,17aR)-3-methyl-1,4-dioxo-1H...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16091((2R,4S)-4-[(4aR,12R,15S,17aS)-15-methyl-14,17-diox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16092((2R,4S)-4-[(4aS,12R,15S,17aR)-15-methyl-14,17-diox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16066(dithia macrocycle compound 25 | tert-butyl N-[(3R,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16063((2S)-2-{[(1R,2R)-2-[(1S,2S)-2-[(2S)-2-[(2S)-2-acet...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BPCPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16071((2R,4S)-4-[(3R,6S,9R)-9-(acetylamino)-6-methyl-5,8...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16072((2R,4S)-4-[(3R,6S,9R)-9-(acetylamino)-6-methyl-5,8...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16079(oxygen-linked macrocycle compound 16 | tert-butyl ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16073((2R,4S)-4-[(5R,8S,11R)-11-(acetylamino)-8-methyl-7...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Universite de Montreal at Succursale Centre-Ville

LigandPNGBDBM16075((2R,4S)-N-butyl-4-hydroxy-2-methyl-4-[(3R,6S,13E)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0KZNPubMed
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