Compile Data Set for Download or QSAR
Found 10 of ic50 for UniProtKB: P15056
TargetSerine/threonine-protein kinase B-raf [409-765](Homo sapiens (Human))
SRMLSC

Curated by PubChem BioAssay
LigandPNGBDBM185589(US9156852, 83 | USRE47451, Example 83)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4N61US Patent
TargetSerine/threonine-protein kinase B-raf [409-765](Homo sapiens (Human))
SRMLSC

Curated by PubChem BioAssay
LigandPNGBDBM185585(US9156852, 16 | USRE47451, Example 16)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4N61US Patent
TargetSerine/threonine-protein kinase B-raf [409-765](Homo sapiens (Human))
SRMLSC

Curated by PubChem BioAssay
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 22nMpH: 8.2 T: 2°CAssay Description:The biochemical activity of compound was determined by incubation with Raf kinases and substrate MEK-1 in the presence of 1-10 uM ATP/ [gamma-32P] AT...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf [409-765](Homo sapiens (Human))
SRMLSC

Curated by PubChem BioAssay
LigandPNGBDBM185588(US9156852, 59 | USRE47451, Example 59)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4N61US Patent
TargetSerine/threonine-protein kinase B-raf [409-765](Homo sapiens (Human))
SRMLSC

Curated by PubChem BioAssay
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf [409-765](Homo sapiens (Human))
SRMLSC

Curated by PubChem BioAssay
LigandPNGBDBM185586(US9156852, 38 | USRE47451, Example 38)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4N61US Patent
TargetSerine/threonine-protein kinase B-raf [409-765](Homo sapiens (Human))
SRMLSC

Curated by PubChem BioAssay
LigandPNGBDBM185584(US9156852, 1 | USRE47451, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 121nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4N61US Patent
TargetSerine/threonine-protein kinase B-raf [409-765](Homo sapiens (Human))
SRMLSC

Curated by PubChem BioAssay
LigandPNGBDBM185587(US9156852, 50 | USRE47451, Example 50)copy SMILEScopy InChI
Affinity DataIC50: 128nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4N61US Patent
TargetSerine/threonine-protein kinase B-raf [409-765](Homo sapiens (Human))
SRMLSC

Curated by PubChem BioAssay
LigandPNGBDBM185590(US9156852, 105 | USRE47451, Example 105)copy SMILEScopy InChI
Affinity DataIC50: 179nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4N61US Patent
TargetSerine/threonine-protein kinase B-raf [409-765](Homo sapiens (Human))
SRMLSC

Curated by PubChem BioAssay
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...)copy SMILEScopy InChI
Affinity DataIC50: 344nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair