Compile Data Set for Download or QSAR
Found 19 of ic50 for UniProtKB: P0A6K3
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50100105(2-(5-Bromo-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-N...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K6CPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50100101(2-(5-Bromo-1-cyclopropylmethyl-2,2-dioxo-1,4-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K6CPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50100094(2-(5-Bromo-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-ben...)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K6CPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50100102(2-(5-Chloro-1-cyclopropylmethyl-2,2-dioxo-1,4-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K6CPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K6CPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50100096(2-(2,2-Dioxo-5-trifluoromethyl-1,4-dihydro-2H-2lam...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K6CPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM21683(N-hydroxy-N-(3-phenylpropyl)formamide | SB-485345)copy SMILEScopy InChI
Affinity DataIC50: 160nMpH: 7.6 T: 2°CAssay Description:Enzyme assay was carried out in 96-well microtiter plates with a SpectraMax plate reader (Molecular Devices Corp.). PDF activity was measured using a...More data for this Ligand-Target Pair
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50100107(CHEMBL53345 | N-Hydroxy-2-(2-oxo-5-trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K6CPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50100108(2-[5-Chloro-2,2-dioxo-1-(3-phenyl-propyl)-1,4-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K6CPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K6CPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50100100(2-(1-Butyl-5-chloro-2,2-dioxo-1,4-dihydro-2H-2lamb...)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K6CPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50100104(2-(2,2-Dioxo-1,4-dihydro-2H-2lambda*6*-benzo[1,2,6...)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K6CPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50100099(2-(5-Fluoro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K6CPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50100103(2-(5-Fluoro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K6CPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM21684(N-[2-(3-benzoylphenoxy)ethyl]-N-hydroxyformamide |...)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+3nMpH: 7.6 T: 2°CAssay Description:Enzyme assay was carried out in 96-well microtiter plates with a SpectraMax plate reader (Molecular Devices Corp.). PDF activity was measured using a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F18X1NPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50100098(CHEMBL54689 | N-Hydroxy-2-(2-oxo-1,4-dihydro-2H-qu...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K6CPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50100106(2-(1-Benzyl-5-chloro-2,2-dioxo-1,4-dihydro-2H-2lam...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K6CPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM21685(N-hydroxy-N-[3-(6-methylpyridin-2-yl)propyl]formam...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMpH: 7.6 T: 2°CAssay Description:Enzyme assay was carried out in 96-well microtiter plates with a SpectraMax plate reader (Molecular Devices Corp.). PDF activity was measured using a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F18X1NPubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50100093((5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-ac...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1K6CPubMed