Affinity DataIC50: 8nMAssay Description:Compound was tested for its binding affinity against Prostaglandin I2 receptor using conventional ligand assay by the displacement of [3H]-iloprost f...More data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Binding affinity to human PGI2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]iloprost from human recombinant IP receptor expressed in HEK293 cells measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]iloprost from human recombinant Prostanoid IP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Compound was tested for prostacyclin (PGI-2) binding by displacement of [3H]-iloprost from human platelets using conventional ligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Agonist activity at human IP receptor in platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1 min follo...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Binding affinity to PGI2 receptor (unknown origin) by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Compound was tested for its binding affinity against Prostaglandin I2 receptor using conventional ligand assay by the displacement of [3H]-iloprost f...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Compound was tested for prostacyclin (PGI-2) binding by displacement of [3H]-iloprost from human platelets using conventional ligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Compound was tested for its inhibitory activity against cathepsin BMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Agonist activity at prostanoid IP receptor (unknown origin) by functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Prostaglandin I2 receptor binding by displacement of [3H]-iloprost from human plateletsMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Agonist activity at prostanoid IP receptor (unknown origin) by functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Compound was tested for its binding affinity against Prostaglandin I2 receptor using conventional ligand assay by the displacement of [3H]-iloprost f...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 53nM EC50: 51nMpH: 7.4 T: 2°CAssay Description:IP receptor binding activity was quantified via a filter binding assay measuring displacement of [3H]-Iloprost binding to human platelet membranes. R...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Agonist activity at human IP receptor in human platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Agonist activity at human IP receptor in human platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Agonist activity at human IP receptor in human platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMpH: 7.4 T: 2°CAssay Description:IP receptor binding activity was quantified via a filter binding assay measuring displacement of [3H]-Iloprost binding to human platelet membranes. R...More data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Agonist activity at PGI2 receptor in Homo sapiens (human) platelets assessed as inhibition of ADP-induced aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Agonist activity at PGI2 in human platelet-rich plasma assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Agonist activity at human IP receptor in human platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 114nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 115nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Agonist activity at human IP receptor in platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1 min follo...More data for this Ligand-Target Pair
Affinity DataIC50: 142nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:IC50 value of the compound was evaluated by measuring the displacement of [3H]-iloprost from Prostaglandin I2 receptorMore data for this Ligand-Target Pair
