Compile Data Set for Download or QSAR
Found 6 of ic50 for UniProtKB: P68431
TargetHistone H3.1 [22-45](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM155253(US10098888, Compound 1 | US9006242, 1)copy SMILES
Affinity DataIC50: 5nMAssay Description:General Materials. S-adenosylmethionine (SAM), S-adenosylhomocyteine (SAH), bicine, KCI, Tween20, dimethylsulfoxide (DMSO) and bovine skin gelatin (B...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1FDQUS Patent
TargetHistone H3.1 [22-45](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM155255(US10098888, Compound 105 | US11642348, Compound 10...)copy SMILEScopy InChI
Affinity DataIC50: 8.40nMAssay Description:General Materials. S-adenosylmethionine (SAM), S-adenosylhomocyteine (SAH), bicine, KCI, Tween20, dimethylsulfoxide (DMSO) and bovine skin gelatin (B...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1FDQUS Patent
TargetHistone H3.1 [22-45](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM155254(US10098888, Compound 2 | US9006242, 2)copy SMILES
Affinity DataIC50: 15nMAssay Description:General Materials. S-adenosylmethionine (SAM), S-adenosylhomocyteine (SAH), bicine, KCI, Tween20, dimethylsulfoxide (DMSO) and bovine skin gelatin (B...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1FDQUS Patent
TargetHistone H3.1 [22-45](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM155253(US10098888, Compound 1 | US9006242, 1)copy SMILES
Affinity DataIC50: 77nMAssay Description:General Materials. S-adenosylmethionine (SAM), S-adenosylhomocyteine (SAH), bicine, KCI, Tween20, dimethylsulfoxide (DMSO) and bovine skin gelatin (B...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1FDQUS Patent
TargetHistone H3.1 [22-45](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM155255(US10098888, Compound 105 | US11642348, Compound 10...)copy SMILEScopy InChI
Affinity DataIC50: 104nMAssay Description:General Materials. S-adenosylmethionine (SAM), S-adenosylhomocyteine (SAH), bicine, KCI, Tween20, dimethylsulfoxide (DMSO) and bovine skin gelatin (B...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1FDQUS Patent
TargetHistone H3.1 [22-45](Homo sapiens (Human))
Epizyme, Inc.

US Patent
LigandPNGBDBM155254(US10098888, Compound 2 | US9006242, 2)copy SMILES
Affinity DataIC50: 110nMAssay Description:General Materials. S-adenosylmethionine (SAM), S-adenosylhomocyteine (SAH), bicine, KCI, Tween20, dimethylsulfoxide (DMSO) and bovine skin gelatin (B...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1FDQUS Patent