Compile Data Set for Download or QSAR
Found 10 of ic50 for UniProtKB: P00533
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27970(1-{4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8BTGPubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27968(4-[4-(4-amino-3-{2-[(2-methoxyphenyl)methyl]-1H-1,...)copy SMILEScopy InChI
Affinity DataIC50: 25nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8BTGPubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27965(3-{2-[(2-methoxyphenyl)methyl]-1H-1,3-benzodiazol-...)copy SMILEScopy InChI
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8BTGPubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27967(ethyl 4-[4-(4-amino-3-{2-[(2-methoxyphenyl)methyl]...)copy SMILEScopy InChI
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8BTGPubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27969(3-{2-[(2-methoxyphenyl)methyl]-1H-1,3-benzodiazol-...)copy SMILEScopy InChI
Affinity DataIC50: 58nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8BTGPubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27964(3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-5-yl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 58nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8BTGPubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27963(3-(2-(2-chlorobenzyl)-1H-benzo[d]imidazol-5-yl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 65nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8BTGPubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27966(1-{4-[4-(4-amino-3-{2-[(2-methoxyphenyl)methyl]-1H...)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8BTGPubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27961(3-(2-benzyl-1H-1,3-benzodiazol-6-yl)-1-[4-(morphol...)copy SMILEScopy InChI
Affinity DataIC50: 270nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8BTGPubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27962(1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-(thiophen-...)copy SMILEScopy InChI
Affinity DataIC50: 361nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8BTGPubMed