Compile Data Set for Download or QSAR
Found 98 of ic50 for UniProtKB: P35557
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.488nMAssay Description:Inhibition of human GCK using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5KB8PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.810nMAssay Description:Inhibition of human GCK using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W380MTPubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50054107(CHEMBL3319533)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50447276(CHEMBL3113985)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241Q5PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50447275(CHEMBL3114185)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241Q5PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50054097(CHEMBL3319540)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053952(CHEMBL3319529)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50054052(CHEMBL3319549)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50054106(CHEMBL3319534)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50447273(CHEMBL3114186)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241Q5PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50447274(CHEMBL3114183)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241Q5PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50054057(CHEMBL3319544)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50054094(CHEMBL3319541)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50054063(CHEMBL3319542)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50447272(CHEMBL3113980)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241Q5PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50054059(CHEMBL3319543)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50447271(CHEMBL3114187)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241Q5PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50548191(CHEMBL4793665)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of human GCK using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X3522NPubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053983(CHEMBL3319551)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50054058(CHEMBL3317472)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053951(CHEMBL3319528)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50447270(CHEMBL3113988)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241Q5PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053971(CHEMBL3319559)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053978(CHEMBL3319554)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50447269(CHEMBL3113989)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241Q5PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053977(CHEMBL3319555)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053954(CHEMBL3319531)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM439303(US10633348, Compound (A-17))copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50054099(CHEMBL3319539)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053974(CHEMBL3319558)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053966(CHEMBL3319560)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50054053(CHEMBL3319548)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50054104(CHEMBL3319535)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50054051(CHEMBL3319550)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50447268(CHEMBL3113990)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241Q5PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50447267(CHEMBL3113987)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241Q5PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053957(CHEMBL3319564)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM439304(US10633348, Compound (A-2))copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053982(CHEMBL3319552)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM438001(US10633348, Compound (A-1) | US10633348, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053950(CHEMBL3319527)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053969(CHEMBL3319561)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053975(CHEMBL3319557)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50054101(CHEMBL3319537)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053979(CHEMBL3319553)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50054054(CHEMBL3319547)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50447266(CHEMBL3113986)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP incubated for 20 mins prior to addition of fluorescein-labeled ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241Q5PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053976(CHEMBL3319556)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053958(CHEMBL3319565)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
TargetHexokinase-4(Homo sapiens (Human))TBA
LigandPNGBDBM50053953(CHEMBL3319530)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JJ3PubMed
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