Compile Data Set for Download or QSAR
Found 358 of ic50 for UniProtKB: P23443
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224498(US10080750, Compound 176 | US9321760, 176 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224487(US10080750, Compound 165 | US9321760, 165 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM364981(6-{3,4-cis-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM364971(4-Amino-6-{3,4-cis-4-[1-(2-azetidin-1-yl-ethyl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM364970(4-Amino-6-{3,4-cis-4-[1-(2-azetidin-1-yl-ethyl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224485(US10080750, Compound 163 | US9321760, 163 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224508(US10080750, Compound 186 | US9321760, 186 | US9662...)copy SMILES
Affinity DataIC50: 1.40nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224340(US10080750, Compound 17 | US9321760, 17 | US966233...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224469(US10080750, Compound 147 | US9321760, 147 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224325(US10080750, Compound 2 | US9321760, 2 | US9662330,...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224460(US10080750, Compound 138 | US9321760, 138 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224526(US10080750, Compound 204 | US9321760, 204 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224326(US10080750, Compound 3 | US9321760, 3 | US9662330,...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224497(US10080750, Compound 175 | US9321760, 175 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224330(US10080750, Compound 7 | US9321760, 7 | US9662330,...)copy SMILES
Affinity DataIC50: 2.80nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224376(US10080750, Compound 53 | US9321760, 53 | US966233...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224517(US10080750, Compound 195 | US9321760, 195 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224375(US10080750, Compound 52 | US9321760, 52 | US966233...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224505(US10080750, Compound 183 | US9321760, 183 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224348(US10080750, Compound 25 | US9321760, 25 | US966233...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224331(US10080750, Compound 8 | US9321760, 8 | US9662330,...)copy SMILES
Affinity DataIC50: 3.40nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224483(US10080750, Compound 161 | US9321760, 161 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224491(US10080750, Compound 169 | US9321760, 169 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224350(US10080750, Compound 27 | US9321760, 27 | US966233...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224481(US10080750, Compound 159 | US9321760, 159 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224327(US10080750, Compound 4 | US9321760, 4 | US9662330,...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224377(US10080750, Compound 54 | US9321760, 54 | US966233...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224462(US10080750, Compound 140 | US9321760, 140 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224380(US10080750, Compound 57 | US9321760, 57 | US966233...)copy SMILES
Affinity DataIC50: 4.70nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224520(US10080750, Compound 198 | US9321760, 198 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224338(US10080750, Compound 15 | US9321760, 15 | US966233...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224339(US10080750, Compound 16 | US9321760, 16 | US966233...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224378(US10080750, Compound 55 | US9321760, 55 | US966233...)copy SMILES
Affinity DataIC50: 5.20nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224347(US10080750, Compound 24 | US9321760, 24 | US966233...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM224525(US10080750, Compound 203 | US9321760, 203 | US9662...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8W9FUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM365731(5-Chloro-6-{(3S,4R)-4-[1-(2-dimethylamino-ethyl)-4...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM365732(6-{(3S,4R)-4-[1-(2-Dimethylamino-ethyl)-4-(4-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM364993(6-{cis-4-[1-(2-Dimethylamino-ethyl)-4-(4-fluoro-3-...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM365734(6-{cis-4-[1-(2-Amino-ethyl)-4-(4-fluoro-3-trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM365735(6-{(3S,4R)-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM365012(6-{cis-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluoro-3-...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM365737(6-{(cis-4-[1-(2-Amino-ethyl)-4-(4-fluoro-3-trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM365738(6-{cis-3-Fluoro-4-[4-(4-fluoro-3-methyl-phenyl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM365739(6-{cis-3-Fluoro-4-[4-(4-fluoro-3-methyl-phenyl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM365740(6-{cis-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluoro-3-...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM365741(4-Amino-6-{(3R,4S)-4-[1-(2-azetidin-1-yl-ethyl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM365742(6-{cis-4-[1-Azetidin-3-ylmethyl-4-(4-fluoro-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM365743(US9867826, Compound 42 | cis-4-[1-(2-Azetidin-1-yl...)copy SMILES
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM365744(US9867826, Compound 43 | cis-4-[1-(2-Azetidin-1-yl...)copy SMILES
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent GmbH

US Patent
LigandPNGBDBM365745(4-Amino-6-{4-[1-(2-azetidin-1-yl-ethyl)-4-(4-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NXMUS Patent
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