Compile Data Set for Download or QSAR
Found 42 of ic50 for UniProtKB: P14646
LigandPNGBDBM50017294(CHEMBL3288029)copy SMILEScopy InChI
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of rat PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2708302PubMed
LigandPNGBDBM50017295(CHEMBL3288030)copy SMILEScopy InChI
Affinity DataIC50: 0.0251nMAssay Description:Inhibition of rat PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2708302PubMed
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibition of phosphodiesterase (PDE) 4BMore data for this Ligand-Target Pair
LigandPNGBDBM50450772(CHEMBL322092)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Inhibition of phosphodiesterase (PDE) 4BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2Z11PubMed
LigandPNGBDBM50450771(CHEMBL326655)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibition of phosphodiesterase (PDE) 4BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2Z11PubMed
LigandPNGBDBM50450770(CHEMBL320307)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Inhibition of phosphodiesterase (PDE) 4BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2Z11PubMed
LigandPNGBDBM50072197(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-6...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50085138(4-[8-(3-Chloro-phenyl)-[1,7]naphthyridin-6-yl]-ben...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58N3GPubMed
LigandPNGBDBM50085135(4-(8-(3-nitrophenyl)-1,7-naphthyridin-6-yl)benzoic...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
LigandPNGBDBM50072195(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50072211(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50085146(8-(3-Nitro-phenyl)-6-pyridin-3-yl-[1,7]naphthyridi...)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58N3GPubMed
LigandPNGBDBM50085139(4-[8-(3-Cyano-phenyl)-[1,7]naphthyridin-6-yl]-benz...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58N3GPubMed
LigandPNGBDBM50085136(8-(3-Nitro-phenyl)-6-phenyl-[1,7]naphthyridine | C...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58N3GPubMed
LigandPNGBDBM50072199(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2,6-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50085140(6-Allyl-8-(3-nitro-phenyl)-[1,7]naphthyridine | CH...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58N3GPubMed
LigandPNGBDBM50072200(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50072194(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-butyl-6...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50085141(CHEMBL351900 | Trifluoro-methanesulfonic acid 8-(3...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58N3GPubMed
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
LigandPNGBDBM50072209(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50085147(8-(3-Nitro-phenyl)-6-o-tolyl-[1,7]naphthyridine | ...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58N3GPubMed
LigandPNGBDBM50085143(CHEMBL158286 | Trifluoro-methanesulfonic acid 8-(3...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58N3GPubMed
LigandPNGBDBM50072204(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethylsu...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50085145(CHEMBL161714 | Trifluoro-methanesulfonic acid 8-(3...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58N3GPubMed
LigandPNGBDBM50085137(6-Furan-2-yl-8-(3-nitro-phenyl)-[1,7]naphthyridine...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58N3GPubMed
LigandPNGBDBM50072205(4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50072206(4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6,7-dimethox...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50072212(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-q...)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50072198(4-(3,5-Diisopropoxy-phenyl)-6,7-dimethoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50072203(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50072210(4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-6-me...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50072208(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
LigandPNGBDBM50085142(8-(3-Nitro-phenyl)-[1,7]naphthyridin-6-ylamine | C...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58N3GPubMed
LigandPNGBDBM50085144(8-(3-Nitro-phenyl)-[1,7]naphthyridine | CHEMBL3519...)copy SMILEScopy InChI
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58N3GPubMed
LigandPNGBDBM50085134((4-Methyl-piperazin-1-yl)-[8-(3-nitro-phenyl)-[1,7...)copy SMILEScopy InChI
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58N3GPubMed
LigandPNGBDBM50072201(5-(6,7-Dimethoxy-2-methyl-quinazolin-4-yl)-benzene...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50072196(2-[2,4-Bis-(3,5-bis-cyclopropylmethoxy-phenyl)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50072207(CHEMBL97213 | [4-(3,5-Bis-cyclopropylmethoxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+4nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50072193(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-7...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed
LigandPNGBDBM50072202(7-Benzyloxy-4-(3,5-bis-cyclopropylmethoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PG1QVXPubMed