Compile Data Set for Download or QSAR
Found 36 of ic50 for UniProtKB: P28702
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Binding affinity against retinoic Acid X beta receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50218464((Z)-4-(5,7,7,10,10-pentamethyl-2-nitro-7,8,9,10-te...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Antagonist activity at RXRbeta (unknown origin) expressed in african green monkey COS1 cells assessed as inhibition of LGD1069-induced agonist activi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MJWPubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50044098(4-[(E)-2-(3-Isopropyl-5,5,8,8-tetramethyl-5,6,7,8-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Binding affinity against retinoic Acid X beta receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8BT5PubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50044099(4-[(E)-2-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Binding affinity against retinoic Acid X beta receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8BT5PubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524173(US11166958, Example 6)copy SMILES
Affinity DataIC50: 87nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524172(US11166958, Example 5)copy SMILES
Affinity DataIC50: 110nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524169(US11166958, Example 2)copy SMILES
Affinity DataIC50: 123nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524182(US11166958, Example 35)copy SMILES
Affinity DataIC50: 197nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524176(US11166958, Example 9)copy SMILES
Affinity DataIC50: 210nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524177(US11166958, Example 18)copy SMILES
Affinity DataIC50: 222nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524179(US11166958, Example 31)copy SMILES
Affinity DataIC50: 524nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524183(US11166958, Example 36)copy SMILES
Affinity DataIC50: 542nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524178(US11166958, Example 30)copy SMILES
Affinity DataIC50: 595nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524181(US11166958, Example 34)copy SMILES
Affinity DataIC50: 644nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524170(US11166958, Example 3)copy SMILES
Affinity DataIC50: 690nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50256177(6-(N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphth...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Antagonist activity at RXRbeta (unknown origin) expressed in african green monkey COS1 cells assessed as inhibition of LGD1069-induced agonist activi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MJWPubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524180(US11166958, Example 33)copy SMILES
Affinity DataIC50: 807nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524175(US11166958, Example 8)copy SMILES
Affinity DataIC50: 856nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50256176(6-(4-chloro-N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Antagonist activity at RXRbeta (unknown origin) expressed in african green monkey COS1 cells assessed as inhibition of LGD1069-induced agonist activi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MJWPubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524168(US11166958, Example 1)copy SMILES
Affinity DataIC50: 968nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against retinoic Acid X beta receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8BT5PubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50032221(4-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against retinoic Acid X beta receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8BT5PubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against retinoic Acid X beta receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20V8BT5PubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524174(US11166958, Example 7)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524171(US11166958, Example 4)copy SMILES
Affinity DataIC50: 1.20E+3nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50256174(6-(4-methyl-N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at RXRbeta (unknown origin) expressed in african green monkey COS1 cells assessed as inhibition of LGD1069-induced agonist activi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MJWPubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50256175(6-(4-methoxy-N-(5,5,8,8-tetramethyl-5,6,7,8-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at RXRbeta (unknown origin) expressed in african green monkey COS1 cells assessed as inhibition of LGD1069-induced agonist activi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MJWPubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524184(WO2015/130905, Example 100)copy SMILES
Affinity DataIC50: 8.89E+3nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524186(WO2015/130905, Example 106)copy SMILES
Affinity DataIC50: 9.26E+3nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524187(WO2015/130905, Example 107)copy SMILES
Affinity DataIC50: 9.26E+3nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM524185(WO2015/130905, Example 105)copy SMILES
Affinity DataIC50: 9.26E+3nMAssay Description:At the assay day cells were washed 3× with assay buffer (as described above), 10 μL buffer remained in the wells after washing. 10 μL Ca ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5K6GUS Patent
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50454190(CHEMBL4202767)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-9-cis-retinoic acid from recombinant human full length RXRbeta after 24 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2SKRPubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50256275(6-(4-nitro-N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at RXRbeta (unknown origin) expressed in african green monkey COS1 cells assessed as inhibition of LGD1069-induced agonist activi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MJWPubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50256123(6-(N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphth...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at RXRbeta (unknown origin) expressed in african green monkey COS1 cells assessed as inhibition of LGD1069-induced agonist activi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MJWPubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50256124(6-(N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphth...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at RXRbeta (unknown origin) expressed in african green monkey COS1 cells assessed as inhibition of LGD1069-induced agonist activi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MJWPubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals, Inc

Curated by ChEMBL
LigandPNGBDBM50276797(CHEMBL4174856)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at recombinant GST-tagged human RXRbeta LBD assessed as inhibition of all-trans-retinoic acid-induced fluorescein-labeled coactiv...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098F7PubMed