Compile Data Set for Download or QSAR
Found 13 of ic50 for UniProtKB: P36506
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498024(CHEMBL3326332)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z322NFPubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498026(CHEMBL3326319)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z322NFPubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498028(CHEMBL3326325)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z322NFPubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498030(CHEMBL3326326)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z322NFPubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50108771(2'-amino-3'-methoxyflavone | 2-(2-Amino-3-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z322NFPubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498023(CHEMBL3326330)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z322NFPubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498025(CHEMBL3326324)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z322NFPubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498021(CHEMBL3326327)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z322NFPubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498027(CHEMBL3326329)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z322NFPubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498019(CHEMBL3326322)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z322NFPubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498029(CHEMBL3326323)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z322NFPubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498022(CHEMBL3326328)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z322NFPubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498020(CHEMBL3326320)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z322NFPubMed