Compile Data Set for Download or QSAR
Found 71 of ic50 for UniProtKB: P10145
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277687(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-me...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277693(2-((2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277686(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(m...)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277702(5-((2-(3-((4-((4-(3-(5-tert-Butyl)-2-methoxy-3-(me...)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277688(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-2-methoxy-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277682(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy)-3...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50295276(2-(2-(2-fluorophenylamino)phenyl)acetic acid | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50295266(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}propanoic a...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277694(US10072034, Example 20(a) | US10072034, Example 20...)copy SMILEScopy InChI
Affinity DataIC50: 10.4nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277685(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)copy SMILEScopy InChI
Affinity DataIC50: 11.7nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277683(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)copy SMILEScopy InChI
Affinity DataIC50: 11.7nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50295267(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}propanamide...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50295281(2-(2-(2-fluorophenoxy)phenyl)acetic acid | CHEMBL2...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50295268(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(methyls...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277696(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)copy SMILEScopy InChI
Affinity DataIC50: 14.4nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277701(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(m...)copy SMILEScopy InChI
Affinity DataIC50: 15.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277690(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-3-(ethylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 16.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277689(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-3-(ethylsulfo...)copy SMILEScopy InChI
Affinity DataIC50: 16.4nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277691(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl) isoxazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 17.2nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277677(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy)-3...)copy SMILEScopy InChI
Affinity DataIC50: 17.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277697(1-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)copy SMILEScopy InChI
Affinity DataIC50: 18.1nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277680(2-(2-(2-(3-((4-((4-(3-(5-tert-Butyl-2-methoxy-3-(m...)copy SMILEScopy InChI
Affinity DataIC50: 18.1nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277694(US10072034, Example 20(a) | US10072034, Example 20...)copy SMILEScopy InChI
Affinity DataIC50: 19.1nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277679(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-(methoxy-d...)copy SMILEScopy InChI
Affinity DataIC50: 19.5nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50295270(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50169048((R)-2-(3-Benzoyl-phenyl)-propionic acid | (R)-2-(3...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277703(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)copy SMILEScopy InChI
Affinity DataIC50: 20.6nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277681(2-(2-(2-(3-(4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 20.8nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277676(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)copy SMILEScopy InChI
Affinity DataIC50: 24.6nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50090679(2-(2-(2,5-dichlorophenylamino)phenyl)acetic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50295269(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N,N'-[3,3-...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277700(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-2-methoxy-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 26.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277684(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-3-(dimethylp...)copy SMILEScopy InChI
Affinity DataIC50: 26.5nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277698(N-(3-(3-(4-((2-((3-(2-(2-(1H-Tetrazol-5-yl)methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 29.2nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277692(N-(5-(tert-Butl-2-methoxy-3-(3-(4-((2-((3-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 29.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50295283(2-[2-(2-Fluorophenoxy)phenyl]-N-(methylsulfonyl)ac...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50169044((-)-ibuprofen | (2R)-2-(4-isobutylphenyl)propanoic...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277699(2-(2-(3-((4-((4-(3-(5-(tert-Buty-2-methoxy-3-(meth...)copy SMILEScopy InChI
Affinity DataIC50: 61.9nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50295287(2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM277678(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B85B49US Patent
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50295275(2-(2-(2-chlorophenylamino)phenyl)acetic acid | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50295282(2-(2-(2-chlorophenoxy)phenyl)acetic acid | CHEMBL3...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50295274(2-(2-(2,6-dichloro-3-methylphenylamino)phenyl)acet...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM59542((1-tosylbenzimidazol-2-yl)amine | 1-(4-methylpheny...)copy SMILEScopy InChI
Affinity DataIC50: 551nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z71QRPCBioAssay
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM59542((1-tosylbenzimidazol-2-yl)amine | 1-(4-methylpheny...)copy SMILEScopy InChI
Affinity DataIC50: 596nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z71QRPCBioAssay
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50295271(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(2,6-dim...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50295272(CHEMBL549975 | N-(tert-Butyl)-2-{2-[(2,6-dichlorop...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
TargetInterleukin-8(Homo sapiens (Human))
Respivert Limited; Topivert Pharma Limited

US Patent
LigandPNGBDBM50295273(3-(2-(2-(2,6-dichlorophenylamino)phenyl)propanamid...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124TWPubMed
Displayed 1 to 50 (of 71 total ) | Next | Last >>
Jump to: