Compile Data Set for Download or QSAR
Found 125 of ic50 for UniProtKB: P27707
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311570(2-(6-(4-(4-aminopyrimidin-2-yloxy)piperidin-1-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440179(CHEMBL2426567)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of [3H]-dC uptake by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311568(3-(6-(4-(4-amino-5-fluoropyrimidin-2-yloxy)piperid...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311564(2-(6-(4-(4-amino-5-fluoropyrimidin-2-yloxy)piperid...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440183(CHEMBL2426563)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9RWPPubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440176(CHEMBL2426570)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptakeMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440176(CHEMBL2426570)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of [3H]-dC uptake by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50031339(CHEMBL3358096)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of [3H]-dC uptake by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29025DMPubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440173(CHEMBL2426573)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptakeMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440173(CHEMBL2426573)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of [3H]-dC uptake by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440177(CHEMBL2426569)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9RWPPubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311609(CHEMBL1080444 | N-((1S,3S)-3-(4-amino-5-fluoro-2-o...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human deoxycytidine kinase by lysate filter binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4HVKPubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311569(2-(6-(4-(4-amino-5-fluoropyrimidin-2-yloxy)piperid...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440184(CHEMBL2426562)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9RWPPubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440179(CHEMBL2426567)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptakeMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440182(CHEMBL2426564)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9RWPPubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440174(CHEMBL2426572)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9RWPPubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440175(CHEMBL2426571)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9RWPPubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440151(CHEMBL2426558)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptakeMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311544(2-(2-(1-(6-(benzo[b]thiophen-2-yl)pyrimidin-4-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311560(2-(6-(4-(4-amino-5-fluoropyrimidin-2-yloxy)piperid...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311556(2-(6-(4-(4-amino-5-fluoropyrimidin-2-yloxy)piperid...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311554(2-(1-(6-(2-chlorophenoxy)pyrimidin-4-yl)piperidin-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311551(2-(1-(6-(biphenyl-2-yloxy)pyrimidin-4-yl)piperidin...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50031337(CHEMBL3358097)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of [3H]-dC uptake by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311566(3-(6-(4-(4-amino-5-fluoropyrimidin-2-yloxy)piperid...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311565(5-fluoro-2-(1-(5-fluoro-6-(4-methoxyphenoxy)pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440172(CHEMBL2426574)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptakeMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440172(CHEMBL2426574)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of [3H]-dC uptake by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311548(5-fluoro-2-(1-(6-(2-methoxyphenoxy)pyrimidin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311567(4-(6-(4-(4-amino-5-fluoropyrimidin-2-yloxy)piperid...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311563(2-(6-(4-(4-amino-5-fluoropyrimidin-2-yloxy)piperid...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311558(5-fluoro-2-(1-(6-(2-fluorophenoxy)pyrimidin-4-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440155(CHEMBL2426598)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptakeMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50031349(CHEMBL3358094)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of [3H]-dC uptake by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440180(CHEMBL2426566)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9RWPPubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311550(5-fluoro-2-(1-(6-(o-tolyloxy)pyrimidin-4-yl)piperi...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311559(2-(1-(6-(4-chloro-2-methylphenoxy)pyrimidin-4-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311562(2-(6-(4-(4-amino-5-fluoropyrimidin-2-yloxy)piperid...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311555(2-(1-(6-(2-ethylphenoxy)pyrimidin-4-yl)piperidin-4...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50031350(CHEMBL3358093)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of [3H]-dC uptake by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440152(CHEMBL2426557)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9RWPPubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50031352(CHEMBL3358091)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Apparent inhibition of human dCK assessed as phosphorylation activity by spectroscopic NADH-dependent enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29025DMPubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440181(CHEMBL2426565)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of [3H]-dC uptake by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440181(CHEMBL2426565)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptakeMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50311557(3-(6-(4-(4-amino-5-fluoropyrimidin-2-yloxy)piperid...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58K9PubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440172(CHEMBL2426574)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Apparent inhibition of human dCK assessed as phosphorylation activity by spectroscopic NADH-dependent enzyme-coupled assayMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440176(CHEMBL2426570)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Apparent inhibition of human dCK assessed as phosphorylation activity by spectroscopic NADH-dependent enzyme-coupled assayMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440173(CHEMBL2426573)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Apparent inhibition of human dCK assessed as phosphorylation activity by spectroscopic NADH-dependent enzyme-coupled assayMore data for this Ligand-Target Pair
TargetDeoxycytidine kinase(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50440181(CHEMBL2426565)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Apparent inhibition of human dCK assessed as phosphorylation activity by spectroscopic NADH-dependent enzyme-coupled assayMore data for this Ligand-Target Pair
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