Compile Data Set for Download or QSAR
Found 33 of ic50 for UniProtKB: P31327
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542023(CHEMBL4649653)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542011(CHEMBL4649844)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542024(CHEMBL4638888)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542023(CHEMBL4649653)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of CPS1 in human pooled hepatocytes assessed as reduction in urea production measured after 16 hrs in presence of NH4Cl by tecan-plate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542019(CHEMBL4634845)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542010(CHEMBL4636473)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542017(CHEMBL4644019)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542016(CHEMBL4634332)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542024(CHEMBL4638888)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CPS1 in human pooled hepatocytes assessed as reduction in urea production measured after 16 hrs in presence of NH4Cl by tecan-plate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542020(CHEMBL4648689)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542018(CHEMBL4639378)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50541999(CHEMBL4649609)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542012(CHEMBL4647643)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542013(CHEMBL4649456)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542027(CHEMBL4641727)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542021(CHEMBL4632591)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542003(CHEMBL4634479)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542004(CHEMBL4642964)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542028(CHEMBL4648273)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+3nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542009(CHEMBL4635675)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542008(CHEMBL4637265)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+3nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542029(CHEMBL4644645)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+3nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542000(CHEMBL4647565)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542006(CHEMBL4643786)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+4nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542002(CHEMBL4644739)copy SMILEScopy InChI
Affinity DataIC50: 1.89E+4nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542001(CHEMBL4633826)copy SMILEScopy InChI
Affinity DataIC50: 2.15E+4nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542025(CHEMBL4648301)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542005(CHEMBL4644707)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+4nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542015(CHEMBL4640145)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+4nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542007(CHEMBL4639689)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+4nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542014(CHEMBL4635338)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+4nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542022(CHEMBL4635298)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+4nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine Inc.

Curated by ChEMBL
LigandPNGBDBM50542026(CHEMBL4639921)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+4nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FVFPubMed