Compile Data Set for Download or QSAR
Found 6 of ic50 for UniProtKB: P18298
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire de chimie bioorganique

LigandPNGBDBM85447(Epoxy analogue, I(a))copy SMILEScopy InChI
Affinity DataKi:  7.00E+3nM ΔG°:  -7.31kcal/mole IC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire de chimie bioorganique

LigandPNGBDBM85448(Epoxy analogue, I(b))copy SMILEScopy InChI
Affinity DataKi:  6.10E+4nM ΔG°:  -5.98kcal/mole IC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BQ4PubMed
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire de chimie bioorganique

LigandPNGBDBM85449(Epoxy analogue, I(c))copy SMILEScopy InChI
Affinity DataKi:  1.05E+5nM ΔG°:  -5.64kcal/mole IC50: 1.10E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BQ4PubMed
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire de chimie bioorganique

LigandPNGBDBM85450(Epithioamino acid analogue, II(a))copy SMILEScopy InChI
Affinity DataKi:  1.00E+5nM ΔG°:  -5.67kcal/mole IC50: 1.40E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BQ4PubMed
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire de chimie bioorganique

LigandPNGBDBM85451(Epithioamino acid analogue, II(b))copy SMILEScopy InChI
Affinity DataKi:  1.40E+5nM ΔG°:  -5.47kcal/mole IC50: 3.00E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BQ4PubMed
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire de chimie bioorganique

LigandPNGBDBM85452(Epithioamino acid analogue, II(c))copy SMILEScopy InChI
Affinity DataKi:  1.40E+5nM ΔG°:  -5.47kcal/mole IC50: 4.00E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BQ4PubMed