Compile Data Set for Download or QSAR
Found 19 of ic50 for UniProtKB: P27867
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50118709(1-{4-[2,6-Dimethyl-4-(4-methyl-[1,3,5]triazin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Concentration required for 50% in vitro activity against rat SDH (sorbitol dehydrogenase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V69HZMPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50113497(1-(4-{(2S,6R)-4-[2-((R)-1-Hydroxy-ethyl)-pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant rat sorbitol dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XS5TPQPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50118706((S)-1-(4-{2,6-Dimethyl-4-[2-(4-methyl-piperazin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Concentration required for 50% in vitro activity against rat SDH (sorbitol dehydrogenase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V69HZMPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50118710(1-(4-{4-[2-(2,4-Dimethyl-imidazol-1-yl)-pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Concentration required for 50% in vitro activity against rat SDH (sorbitol dehydrogenase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V69HZMPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50113491(1-(4-{(3S,5R)-4-[2-(1-Hydroxy-ethyl)-pyrimidin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant rat Sorbitol dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XS5TPQPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50118711(1-{4-[4-(4,6-Dimethyl-[1,3,5]triazin-2-yl)-2,6-dim...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Concentration required for 50% in vitro activity against rat SDH (sorbitol dehydrogenase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V69HZMPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50118711(1-{4-[4-(4,6-Dimethyl-[1,3,5]triazin-2-yl)-2,6-dim...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Concentration required for 50% in vitro activity against rat SDH (sorbitol dehydrogenase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V69HZMPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50118708(1-{4-[2,6-Dimethyl-4-(4-phenyl-[1,3,5]triazin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Concentration required for 50% in vitro activity against rat SDH (sorbitol dehydrogenase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V69HZMPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50118712(1-(4-{2,6-Dimethyl-4-[2-(4-methyl-imidazol-1-yl)-p...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Concentration required for 50% in vitro activity against rat SDH (sorbitol dehydrogenase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V69HZMPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50113496((S)-1-(4-{(3S,5R)-4-[2-((R)-1-Hydroxy-ethyl)-pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Concentration required for 50% in vitro activity against rat SDH (sorbitol dehydrogenase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V69HZMPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50113494((R)-1-(4-{(3S,5R)-4-[2-((R)-1-Hydroxy-ethyl)-pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant rat sorbitol dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XS5TPQPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50113493(1-(4-{(3S,5R)-4-[2-((R)-1-Hydroxy-ethyl)-pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant rat sorbitol dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XS5TPQPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50118713(1-{4-[4-(4-Hydroxymethyl-6-methyl-[1,3,5]triazin-2...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Concentration required for 50% in vitro activity against rat SDH (sorbitol dehydrogenase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V69HZMPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50113498((R)-1-(4-{(3S,5R)-4-[2-((S)-1-Hydroxy-ethyl)-pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant rat Sorbitol dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XS5TPQPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50113496((S)-1-(4-{(3S,5R)-4-[2-((R)-1-Hydroxy-ethyl)-pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant rat sorbitol dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XS5TPQPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50409605(CHEMBL2111939)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Concentration required for 50% in vitro activity against rat SDH (sorbitol dehydrogenase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V69HZMPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50118707(1-{4-[2,6-Dimethyl-4-(4-methyl-6-phenyl-[1,3,5]tri...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Concentration required for 50% in vitro activity against rat SDH (sorbitol dehydrogenase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V69HZMPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50113492(1-{4-[(3S,5R)-4-(2-Acetyl-pyrimidin-4-yl)-3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 227nMAssay Description:Inhibition of recombinant rat sorbitol dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XS5TPQPubMed
TargetSorbitol dehydrogenase(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50113495((S)-1-(4-{(3S,5R)-4-[2-((S)-1-Hydroxy-ethyl)-pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Inhibition of recombinant rat Sorbitol dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XS5TPQPubMed