Compile Data Set for Download or QSAR
Found 42 of ic50 for UniProtKB: P36873
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50061067(15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in E275RMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50061067(15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in wild typeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50061067(15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in D220VMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110681(CHEMBL430266 | Calyculin-A)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in D220VMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110681(CHEMBL430266 | Calyculin-A)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in E275RMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110681(CHEMBL430266 | Calyculin-A)copy SMILEScopy InChI
Affinity DataIC50: 0.450nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in wild typeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50061067(15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 0.560nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in C127SMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50061067(15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in Y272FMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50061067(15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in D208AMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110681(CHEMBL430266 | Calyculin-A)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in C127SMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110676(CHEMBL280487 | okadaic acid)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against serine/threonine protein phosphatase 1(PP1)More data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110676(CHEMBL280487 | okadaic acid)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type D220V by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50061067(15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 9PP1) mutants by natural toxins in R221SMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50061067(15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in H248NMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50061067(15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in R96AMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110676(CHEMBL280487 | okadaic acid)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in wild typeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110681(CHEMBL430266 | Calyculin-A)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in Y272FMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110676(CHEMBL280487 | okadaic acid)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type E275R by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110681(CHEMBL430266 | Calyculin-A)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in R96AMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110676(CHEMBL280487 | okadaic acid)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type C127S by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50061067(15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in N124DMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50177318(2-(4-(7-(4-tetradecylbenzoyl)cyclopenta[d][1,2]oxa...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against Protein phosphatase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319VFGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110676(CHEMBL280487 | okadaic acid)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type R96A by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110681(CHEMBL430266 | Calyculin-A)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in R221SMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110681(CHEMBL430266 | Calyculin-A)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in D208AMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110681(CHEMBL430266 | Calyculin-A)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in H248NMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110681(CHEMBL430266 | Calyculin-A)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in N124DMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110676(CHEMBL280487 | okadaic acid)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type Y272F by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50177316(2-(4-(7-(4-(aminomethyl)benzoyl)cyclopenta[d][1,2]...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against Protein phosphatase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319VFGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50090505((1R,2S,6R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2...)copy SMILEScopy InChI
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 by anhydride modified Cantharidin analoguesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110696(4,10-Dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione ...)copy SMILEScopy InChI
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 by anhydride modified Cantharidin analoguesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110692(7-Oxa-bicyclo[2.2.1]heptane-2,3-dicarboxylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 2.96E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 by anhydride modified Cantharidin analoguesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110695(7-Oxa-bicyclo[2.2.1]heptane-2,3-dicarboxylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 4.71E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 by anhydride modified Cantharidin analoguesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110698(7-Oxa-bicyclo[2.2.1]heptane-2,3-dicarboxylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 4.82E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 by anhydride modified Cantharidin analoguesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110676(CHEMBL280487 | okadaic acid)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type D208A by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110676(CHEMBL280487 | okadaic acid)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type N124D by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110676(CHEMBL280487 | okadaic acid)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type H248N by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110676(CHEMBL280487 | okadaic acid)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type R221S by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50177317(2-(4-(7-(4-methoxybenzoyl)cyclopenta[d][1,2]oxazin...)copy SMILEScopy InChI
Affinity DataIC50: 3.52E+4nMAssay Description:Inhibitory activity against Protein phosphatase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319VFGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50090506((1R,2S,6R,7S)-5-Ethoxy-4,10-dioxa-tricyclo[5.2.1.0...)copy SMILEScopy InChI
Affinity DataIC50: 7.46E+5nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 by anhydride modified Cantharidin analoguesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50090508((1R,2S,6R,7S)-5-Methoxy-4,10-dioxa-tricyclo[5.2.1....)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 by anhydride modified Cantharidin analoguesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50090507((1R,2S,6R,7S)-5-Propoxy-4,10-dioxa-tricyclo[5.2.1....)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 by anhydride modified Cantharidin analoguesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5GCGPubMed