Compile Data Set for Download or QSAR
Found 40 of ic50 for UniProtKB: P42346
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315095(1-(4-(4,6-bis((R)-3-methylmorpholino)-1,3,5-triazi...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315097(1-(4-(4,6-bis((R)-3-methylmorpholino)-1,3,5-triazi...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315219(1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ402XPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315088(4-(3-(4-(4,6-bis((R)-3-methylmorpholino)-1,3,5-tri...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315087(1-(4-(4,6-bis((R)-3-methylmorpholino)-1,3,5-triazi...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315096((R)-1-(4-(4-(3-methylmorpholino)-6-(tetrahydro-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315085(1-(4-(4,6-bis((R)-3-methylmorpholino)-1,3,5-triazi...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315090((R)-1-(4-(4-(3-methylmorpholino)-6-(tetrahydro-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315082((R)-1-(4-(4-isopropylpiperazine-1-carbonyl)phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315091((R)-1-(4-(4-(3-methylmorpholino)-6-(tetrahydro-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315093((R)-1-(4-(4-(3-methylmorpholino)-6-(tetrahydro-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315047(1-(4-(4,6-di(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ402XPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315099(1-(4-(4,6-bis((R)-3-methylmorpholino)-1,3,5-triazi...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315092((R)-1-(4-(4-(dimethylamino)piperidin-1-yl)phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315209(1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ402XPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315098(1-(4-(4,6-bis((R)-3-methylmorpholino)-1,3,5-triazi...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315086(1-(4-(4,6-bis((R)-3-methylmorpholino)-1,3,5-triazi...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315083(1-(4-(4,6-bis((R)-3-methylmorpholino)-1,3,5-triazi...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315212(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-(3...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ402XPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315084(1-(4-(4,6-bis((R)-3-methylmorpholino)-1,3,5-triazi...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315089((R)-1-(4-(4-(3-methylmorpholino)-6-(tetrahydro-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315216(1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ402XPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315218(1-cyclopropyl-3-(4-(4,6-di(8-oxa-3-azabicyclo[3.2....)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ402XPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315217(1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ402XPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315094(1-(4-(4-((1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HQ5PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50520428(CHEMBL4518369)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of mTOR L1460P mutant in rat primary cortical neuron assessed as reduction in PS6 phosphorylation incubated for 4 hrs by Western blot anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VFWPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50520428(CHEMBL4518369)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of mTOR S2215Y mutant in rat primary cortical neuron assessed as reduction in PS6 phosphorylation incubated for 4 hrs by Western blot anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VFWPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50520428(CHEMBL4518369)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of mTOR S2215F mutant in rat primary cortical neuron assessed as reduction in PS6 phosphorylation incubated for 4 hrs by Western blot anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VFWPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50520428(CHEMBL4518369)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of mTOR in rat primary cortical neuron assessed as reduction in PS6 phosphorylation incubated for 4 hrs by Western blot analysis (Rvb = 19...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VFWPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50591240(CHEMBL5204586)copy SMILES
Affinity DataIC50: 21nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3WN7PubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50520428(CHEMBL4518369)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of mTOR E2419K mutant in rat primary cortical neuron assessed as reduction in PS6 phosphorylation incubated for 4 hrs by Western blot anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VFWPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50520428(CHEMBL4518369)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of mTOR L2427P mutant in rat primary cortical neuron assessed as reduction in PS6 phosphorylation incubated for 4 hrs by Western blot anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VFWPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315211(1-(4-(4,6-di((1S,4S)-2-oxa-5-azabicyclo[2.2.1]hept...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ402XPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50520428(CHEMBL4518369)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of mTOR C1483Y mutant in rat primary cortical neuron assessed as reduction in PS6 phosphorylation incubated for 4 hrs by Western blot anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1VFWPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315214(3,3'-(6-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ402XPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ402XPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315215(3-(4-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ402XPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315210(1-(4-(4,6-di((1R,4R)-2-oxa-5-azabicyclo[2.2.1]hept...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ402XPubMed
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein kinase mTOR(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of rat derived mTOR using [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84DJ7PubMed