Compile Data Set for Download or QSAR
Found 249 of ic50 for UniProtKB: P36544
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170589((3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha 7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170586((3S)-3-{[(2S)-1-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha7; Range is 0.3-1.5 nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50393253(CHEMBL2151573)copy SMILEScopy InChI
Affinity DataIC50: 1.09nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus oocyteMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P32QPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50140089(CHEMBL437423 | GCCSHPACAGNNQHIC*)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha 7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50597512(CHEMBL5201239)copy SMILES
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J96BDGPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50597513(CHEMBL5178473)copy SMILES
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J96BDGPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170592(CHEMBL411146)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha7; Range is 0.3-1.5 nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50597506(CHEMBL5190813)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J96BDGPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM80642(CHEMBL191491 | MG 624 | MLS002172460 | SMR00125409...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J96BDGPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50597507(CHEMBL5176101)copy SMILES
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J96BDGPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50597505(CHEMBL5174508)copy SMILES
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J96BDGPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50597504(CHEMBL5177606)copy SMILES
Affinity DataIC50: 2.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J96BDGPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170584(CHEMBL411145)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha-7 Range is 3-5 nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50175606(CHEMBL3302240)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SPQPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50466614(CHEMBL4291079)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P2WPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50140087(CHEMBL265198 | GCCSNPVCHLEHSNLC*)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha7; Range is 0.5-8 nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50366779(METHYLLYCACONITINE)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Antagonist activity at human alpha-7 nAChR in tsA201 cells coexpressed with Ric3 by FMP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67HRCPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50366779(METHYLLYCACONITINE)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Antagonist activity at human alpha7nAChR co-expressed with human Ric3 in tsA201 cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67HRCPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50339937(1,1',1''-(5,5',5''-(benzene-1,3,5-triyl)tris(penta...)copy SMILEScopy InChI
Affinity DataIC50: 8.80nMAssay Description:Antagonist activity at alpha7 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9XN9PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170600((3S)-3-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(...)copy SMILEScopy InChI
Affinity DataIC50: 9.60nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha 7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50175589(CHEMBL3302229)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SPQPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50466607(CHEMBL4293646)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P2WPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50175603(CHEMBL3303977)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SPQPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50528722(CHEMBL4453847)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Induction of desensitization at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine induced current treate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7SZRPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50590141(CHEMBL5176133)copy SMILES
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3X9GPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50466606(CHEMBL4280452)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P2WPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170588(CHEMBL451252)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha 7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50049757(()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of [3H]alpha-BGT binding to alpha7 nicotinic acetylcholine receptor in Homo sapiens (human) SH-SY5Y cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM80642(CHEMBL191491 | MG 624 | MLS002172460 | SMR00125409...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P2WPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50466613(CHEMBL4287656)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P2WPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170603((3S)-3-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha 7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50514670(CHEMBL4555265)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents by two-electrode voltage clamp ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89GSKPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50597510(CHEMBL5176690)copy SMILES
Affinity DataIC50: 78nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J96BDGPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50587094(CHEMBL5083247)copy SMILES
Affinity DataIC50: 86nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78K4QPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50339936(2,2',2''-(5,5',5''-(benzene-1,3,5-triyl)tris(penta...)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:Antagonist activity at alpha7 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9XN9PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50466608(CHEMBL4285772)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P2WPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50339938(1,1',1'',1'''-(5,5',5'',5'''-(benzene-1,2,4,5-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Antagonist activity at alpha7 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9XN9PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50445327(CHEMBL3104240)copy SMILEScopy InChI
Affinity DataIC50: 103nMAssay Description:Inhibition of alpha7 nAChR (unknown origin) expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z171MPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM80642(CHEMBL191491 | MG 624 | MLS002172460 | SMR00125409...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha 7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)copy SMILES
Affinity DataIC50: 115nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3Q8VPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50339935(1,1',1''-(5,5',5''-(benzene-1,3,5-triyl)tris(penta...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Antagonist activity at alpha7 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9XN9PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50590140(CHEMBL5202162)copy SMILES
Affinity DataIC50: 176nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3X9GPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50339933(1,1',1'',1'''-(5,5',5'',5'''-(benzene-1,2,4,5-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 185nMAssay Description:Antagonist activity at alpha7 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9XN9PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50581246(CHEMBL5080428)copy SMILES
Affinity DataIC50: 186nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542SG3PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170593((3S)-3-[(2S)-2-[(2R)-2-[(2R)-2-(2-aminoacetamido)-...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha7; Range is 100-200 nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G79PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50485643(3-Phenylquinuclidine | CHEMBL1890808)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]epibatidine from chimeric human alpha7-5-HT3A receptor expressed in HEK293 cells after 2 hrs by scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73HMSPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50601896(CHEMBL5203781)copy SMILES
Affinity DataIC50: 259nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49T6PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50601896(CHEMBL5203781)copy SMILES
Affinity DataIC50: 266nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49T6PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50220056((1S,9R,18R,19S,21R,22R,23R,25R,32S,34R,35R,36S)-24...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Antagonist activity at human alpha-7 nAChR in tsA201 cells coexpressed with Ric3 by FMP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67HRCPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50459888(CHEMBL4225157)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus oocytes at -80 mV holding potential by electro-physiological analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC92NRPubMed
Displayed 1 to 50 (of 249 total ) | Next | Last >>
Jump to: