Compile Data Set for Download or QSAR
Found 1487 of ic50 for UniProtKB: P40763
LigandPNGBDBM50408828(CHEMBL5270588)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50588525(CHEMBL5177956)copy SMILES
Affinity DataIC50: 5.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78J1PubMed
LigandPNGBDBM50588528(CHEMBL5209107)copy SMILES
Affinity DataIC50: 5.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78J1PubMed
TargetSignal transducer and activator of transcription 3 [702-738,740-752](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43584(2-[(1-methyl-2-benzimidazolyl)methylamino]phenol |...)copy SMILEScopy InChI
Affinity DataIC50: 8.49nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QBKPCBioAssay
LigandPNGBDBM50588530(CHEMBL5201151)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78J1PubMed
LigandPNGBDBM50545650(Delgocitinib | JTE-052 | JTE-052A | LEO 124249 | L...)copy SMILEScopy InChI
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50588531(CHEMBL5171007)copy SMILES
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78J1PubMed
LigandPNGBDBM50588507(CHEMBL5178622)copy SMILES
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78J1PubMed
LigandPNGBDBM50335201(5-Chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of Stat3 phosphorylation in human SET2 cells after 1 hr by Western blottingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32WRMPubMed
TargetSignal transducer and activator of transcription 3 [702-738,740-752](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43560(4-acetyl-N-(2-methoxyphenyl)-3,5-dimethyl-1H-pyrro...)copy SMILEScopy InChI
Affinity DataIC50: 25.5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QBKPCBioAssay
LigandPNGBDBM50588526(CHEMBL5189135)copy SMILES
Affinity DataIC50: 28nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78J1PubMed
LigandPNGBDBM50590873(CHEMBL5176684)copy SMILES
Affinity DataIC50: 28nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF6006PubMed
LigandPNGBDBM50588514(CHEMBL5184385)copy SMILES
Affinity DataIC50: 31nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78J1PubMed
LigandPNGBDBM50590921(CHEMBL5176948)copy SMILES
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF6006PubMed
LigandPNGBDBM50545650(Delgocitinib | JTE-052 | JTE-052A | LEO 124249 | L...)copy SMILEScopy InChI
Affinity DataIC50: 33nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50612060(CHEMBL5279856)copy SMILES
Affinity DataIC50: 35nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50588527(CHEMBL5201419)copy SMILES
Affinity DataIC50: 36nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78J1PubMed
LigandPNGBDBM50590882(CHEMBL5182844)copy SMILES
Affinity DataIC50: 37nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF6006PubMed
LigandPNGBDBM50588529(CHEMBL5209399)copy SMILES
Affinity DataIC50: 38nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78J1PubMed
LigandPNGBDBM50588524(CHEMBL5205645)copy SMILES
Affinity DataIC50: 39nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78J1PubMed
LigandPNGBDBM50588518(CHEMBL5175035)copy SMILES
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78J1PubMed
LigandPNGBDBM50590914(CHEMBL5199234)copy SMILES
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF6006PubMed
LigandPNGBDBM50590895(CHEMBL5185530)copy SMILES
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF6006PubMed
LigandPNGBDBM50545650(Delgocitinib | JTE-052 | JTE-052A | LEO 124249 | L...)copy SMILEScopy InChI
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 44nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50588532(CHEMBL5200170)copy SMILES
Affinity DataIC50: 46nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78J1PubMed
LigandPNGBDBM50590923(CHEMBL5196490)copy SMILES
Affinity DataIC50: 52nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF6006PubMed
LigandPNGBDBM50590919(CHEMBL5189947)copy SMILES
Affinity DataIC50: 58nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF6006PubMed
LigandPNGBDBM50590911(CHEMBL5170615)copy SMILES
Affinity DataIC50: 60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF6006PubMed
LigandPNGBDBM50590879(CHEMBL5182625)copy SMILES
Affinity DataIC50: 64nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF6006PubMed
LigandPNGBDBM50588505(CHEMBL5206754)copy SMILES
Affinity DataIC50: 64nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78J1PubMed
LigandPNGBDBM50569071(CHEMBL4846365)copy SMILES
Affinity DataIC50: 67nMAssay Description:Inhibition of IL-6 induced STAT3 transcriptional activity in human HepG2 cells incubated for 1 hr followed by stimulation with IL-6 for 5.5 hrs by lu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP571BPubMed
LigandPNGBDBM50300648(4-(3-((S)-1-((cis)-2-((S)-5-amino-1-(benzylamino)-...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of Stat3 SH2 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M045HHPubMed
LigandPNGBDBM50300658(4-((E)-3-((S)-1-((1R,2S,5S)-2-(2-(benzyloxy)ethylc...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of Stat3 SH2 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M045HHPubMed
LigandPNGBDBM50300657(4-(3-((S)-1-((cis)-2-((2R,3S)-6-amino-2-(benzyloxy...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of Stat3 SH2 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M045HHPubMed
LigandPNGBDBM50588501(CHEMBL5193538)copy SMILES
Affinity DataIC50: 72nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78J1PubMed
LigandPNGBDBM50588506(CHEMBL5201590)copy SMILES
Affinity DataIC50: 76nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78J1PubMed
LigandPNGBDBM50590920(CHEMBL5171708)copy SMILES
Affinity DataIC50: 76nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF6006PubMed
TargetSignal transducer and activator of transcription 3 [702-738,740-752](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43604(MLS000522376 | N-(4-chloranyl-2,5-dimethoxy-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QBKPCBioAssay
TargetSignal transducer and activator of transcription 3 [702-738,740-752](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43595(MLS000104263 | N-(1-acetyl-2-chloro-3-indolyl)acet...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QBKPCBioAssay
LigandPNGBDBM50335201(5-Chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of Stat3 phosphorylation in human HEL cells after 1 hr by Western blottingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32WRMPubMed
LigandPNGBDBM50545650(Delgocitinib | JTE-052 | JTE-052A | LEO 124249 | L...)copy SMILEScopy InChI
Affinity DataIC50: 84nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50590889(CHEMBL5177332)copy SMILES
Affinity DataIC50: 88nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF6006PubMed
LigandPNGBDBM50590909(CHEMBL5189774)copy SMILES
Affinity DataIC50: 93nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF6006PubMed
LigandPNGBDBM50590916(CHEMBL5183263)copy SMILES
Affinity DataIC50: 94nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF6006PubMed
LigandPNGBDBM50300656(4-(3-((S)-1-((cis)-2-((S)-5-amino-1-(benzyloxy)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Inhibition of Stat3 SH2 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M045HHPubMed
LigandPNGBDBM420304(LLL-12)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Inhibition of IL-6 induced STAT3 transcriptional activity in human HepG2 cells incubated for 1 hr followed by stimulation with IL-6 for 5.5 hrs by lu...More data for this Ligand-Target Pair
Ligand InfoPurchaseMCE
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP571BPubMed
LigandPNGBDBM50588512(CHEMBL5201252)copy SMILES
Affinity DataIC50: 101nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB78J1PubMed
LigandPNGBDBM50213228(2-(4-((S)-3-((S)-1-((S)-2-(((S)-5-amino-1-((2S,3R)...)copy SMILEScopy InChI
Affinity DataIC50: 108nMAssay Description:Inhibition of STAT3 dimer DNA binding activity by ELISA after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736QMVPubMed
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