Compile Data Set for Download or QSAR
Found 35 of ic50 for UniProtKB: P0C6X6
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM525229(N-[(1S)-1-(1-bicyclo[1.1.1]pentanylmethyl)-2-[2-[(...)copy SMILES
Affinity DataIC50: 11nMAssay Description: For the HCoV-OC433CLpro assay, 2 μL of 0.02 μM recombinant HCoV-OC433CL protease were mixed with serial dilutions of each comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF30BVPubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM525230(WO2022043374, Example 72)copy SMILES
Affinity DataIC50: 13nMAssay Description: For the HCoV-OC433CLpro assay, 2 μL of 0.02 μM recombinant HCoV-OC433CL protease were mixed with serial dilutions of each comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF30BVPubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM525228(N-[(1S)-2-[2-[(2R)-2-chloro-2-fluoro-acetyl]-2-[[(...)copy SMILES
Affinity DataIC50: 15nMAssay Description: For the HCoV-OC433CLpro assay, 2 μL of 0.02 μM recombinant HCoV-OC433CL protease were mixed with serial dilutions of each comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF30BVPubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM525176(N-[(1S)-1-[[(3-amino-3-oxo-propyl)-(2-chloroacetyl...)copy SMILES
Affinity DataIC50: 17nMAssay Description: For the HCoV-OC433CLpro assay, 2 μL of 0.02 μM recombinant HCoV-OC433CL protease were mixed with serial dilutions of each comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF30BVPubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM525251(N-[(1S)-2-[2-[(2R)-2-chloro-2-fluoro-acetyl]-2-[[(...)copy SMILES
Affinity DataIC50: 17nMAssay Description: For the HCoV-OC433CLpro assay, 2 μL of 0.02 μM recombinant HCoV-OC433CL protease were mixed with serial dilutions of each comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF30BVPubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM525203(N-[(1S)-1-[[(2-Chloroacetyl)-[(2-oxo-pyrrolidin-3-...)copy SMILES
Affinity DataIC50: 19nMAssay Description: For the HCoV-OC433CLpro assay, 2 μL of 0.02 μM recombinant HCoV-OC433CL protease were mixed with serial dilutions of each comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF30BVPubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM525250(N-[(1S)-1-(1-bicyclo[1.1.1]pentanylmethyl)-2-[2-[(...)copy SMILES
Affinity DataIC50: 21nMAssay Description: For the HCoV-OC433CLpro assay, 2 μL of 0.02 μM recombinant HCoV-OC433CL protease were mixed with serial dilutions of each comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF30BVPubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM525252(N-[(1S)-1-[[[(2R)-2-chloro-2-fluoro-acetyl]-[[(3S)...)copy SMILES
Affinity DataIC50: 23nMAssay Description: For the HCoV-OC433CLpro assay, 2 μL of 0.02 μM recombinant HCoV-OC433CL protease were mixed with serial dilutions of each comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF30BVPubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM448319(GC-376 | GC376)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8GWQPubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM525253(WO2022043374, Example 73)copy SMILES
Affinity DataIC50: 41nMAssay Description: For the HCoV-OC433CLpro assay, 2 μL of 0.02 μM recombinant HCoV-OC433CL protease were mixed with serial dilutions of each comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF30BVPubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM484194(UAWJ9-36-1)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8GWQPubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM484195(UAWJ9-36-3)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8GWQPubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420980(US9975885, Compound 37)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420974(US9975885, Compound 30)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420977(US9975885, Compound 32)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420960(US9975885, Compound 19)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420981(US9975885, Compound 64)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420975(US9975885, Compound 31)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420337(US9975885, Compound 1P)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420996(US9975885, Compound 77)copy SMILES
Affinity DataIC50: 7.00E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420978(US9975885, Compound 33)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420993(US9975885, Compound 47)copy SMILES
Affinity DataIC50: 7.70E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420979(US9975885, Compound 34)copy SMILEScopy InChI
Affinity DataIC50: 8.90E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420349(US9975885, Compound 6)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420973(US9975885, Compound 29)copy SMILEScopy InChI
Affinity DataIC50: 1.11E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420990(US9975885, Compound 43)copy SMILES
Affinity DataIC50: 1.24E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420987(US9975885, Compound 40)copy SMILES
Affinity DataIC50: 1.37E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420983(US9975885, Compound 3P | med.21724, Compound 125)copy SMILES
Affinity DataIC50: 1.37E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420991(US9975885, Compound 44)copy SMILES
Affinity DataIC50: 1.56E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420972(US9975885, Compound 27)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420985(US9975885, Compound 38)copy SMILES
Affinity DataIC50: 2.44E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420961(US9975885, Compound 2P | acs.jmedchem.1c00409_ST.4...)copy SMILEScopy InChI
Affinity DataIC50: 2.44E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420992(US9975885, Compound 46)copy SMILES
Affinity DataIC50: 2.45E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420994(US9975885, Compound 48)copy SMILES
Affinity DataIC50: 4.65E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)TBA
LigandPNGBDBM420989(US9975885, Compound 42)copy SMILES
Affinity DataIC50: 6.31E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ63XXUS Patent