TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 2.40nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 15nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 19nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 22.5nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 26nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 46nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 55nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 69nMAssay Description:Inhibition of rat Nav1.4 expressed in HEK293 cells at -80 mV holding potential by whole cell patch-clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 83nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 87nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 90nMAssay Description:Inhibition of rat Nav1.4 channel expressed in Xenopus oocytes by whole cell voltage clamp techniqueMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 135nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 230nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 500nMAssay Description:Inhibition of rat skeletal muscle Nav1.4 expressed in HEK293 cells by whole cell voltage clamp methodMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of rat Nav1.4 expressed in HEK293 cells at -80 mV holding potential by whole cell patch-clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of rat Nav1.4 expressed in HEK293 cells at -80 mV holding potential by whole cell patch-clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of rat Nav1.4 expressed in HEK293 cells at -80 mV holding potential by whole cell patch-clamp assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 5.43E+4nMAssay Description:Inhibition of rat Nav1.4 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 2.04E+5nMAssay Description:Inhibition of rat Nav1.4 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of the Leland Stanford Junior University
US Patent
The Board of Trustees of the Leland Stanford Junior University
US Patent
Affinity DataIC50: 6.00E+5nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
