Compile Data Set for Download or QSAR
Found 9 of ic50 for UniProtKB: P11678
TargetEosinophil peroxidase(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50106515(7-Benzyloxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human EPX bromination activity assessed as reduction in H2O2 catalyzed 3-bromo tyrosine formation from tyrosine and potassium bromide p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W0997ZPubMed
TargetEosinophil peroxidase(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50507390(CHEMBL4482878 | US10981879, Example 3)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human EPX bromination activity assessed as reduction in H2O2 catalyzed 3-bromo tyrosine formation from tyrosine and potassium bromide p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W0997ZPubMed
TargetEosinophil peroxidase(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM357629(7-benzyl-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine ...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human EPX bromination activity using tyrosine as substrate by measuring 3-bromo tyrosine formation incubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4829PubMed
TargetEosinophil peroxidase(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM434842(7-{18-oxa-3,4,10-triazatetracyclo[17.3.1.13,6.113,...)copy SMILES
Affinity DataIC50: 37nMAssay Description:EPX bromination activity was measured in 100 mM KPi (pH 7.4) by monitoring the H2O2 catalyzed formation of 3-bromo tyrosine from tyrosine and potassi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D8BUS Patent
TargetEosinophil peroxidase(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM434844(7-{14′-Oxa-3′,4′,10′-triaz...)copy SMILES
Affinity DataIC50: 63nMAssay Description:EPX bromination activity was measured in 100 mM KPi (pH 7.4) by monitoring the H2O2 catalyzed formation of 3-bromo tyrosine from tyrosine and potassi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D8BUS Patent
TargetEosinophil peroxidase(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50554034(CHEMBL4747269)copy SMILES
Affinity DataIC50: 92nMAssay Description:Inhibition of human EPX bromination activity using tyrosine as substrate by measuring 3-bromo tyrosine formation incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4829PubMed
TargetEosinophil peroxidase(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM434841(7-{18-oxa-3,4,10-triazatetracyclo[17.3.1.13,6.112,...)copy SMILES
Affinity DataIC50: 190nMAssay Description:EPX bromination activity was measured in 100 mM KPi (pH 7.4) by monitoring the H2O2 catalyzed formation of 3-bromo tyrosine from tyrosine and potassi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D8BUS Patent
TargetEosinophil peroxidase(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM434843(7-{3-Oxa-10,11,17-triazatetracyclo[16.2.2.14,8.110...)copy SMILES
Affinity DataIC50: 220nMAssay Description:EPX bromination activity was measured in 100 mM KPi (pH 7.4) by monitoring the H2O2 catalyzed formation of 3-bromo tyrosine from tyrosine and potassi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D8BUS Patent
TargetEosinophil peroxidase(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50554035(CHEMBL4790231)copy SMILES
Affinity DataIC50: 360nMAssay Description:Inhibition of human EPX bromination activity using tyrosine as substrate by measuring 3-bromo tyrosine formation incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4829PubMed