Compile Data Set for Download or QSAR
Found 44 of ic50 for UniProtKB: P11275
LigandPNGBDBM50168283((3-hydroxyphenyl)acetic acid | (m-hydroxyphenyl)ac...)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ72VWPubMed
LigandPNGBDBM16426(2-(2-hydroxyphenyl)acetic acid | 2-Hydroxyphenylac...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ72VWPubMed
LigandPNGBDBM6838(1-(2-{18-methyl-12,14-dioxo-3,13,18-triazahexacycl...)copy SMILEScopy InChI
Affinity DataIC50: 25nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6840(5-[2-(4-hydroxypiperidin-1-yl)ethyl]-18-methyl-3,1...)copy SMILEScopy InChI
Affinity DataIC50: 46nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6846(5-{2-[(4-hydroxycyclohexyl)amino]ethyl}-18-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 49nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6858(8-bromo-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^...)copy SMILEScopy InChI
Affinity DataIC50: 58nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BCNPubMed
LigandPNGBDBM6842(18-methyl-5-[2-(piperidin-1-yl)ethyl]-3,13,18-tria...)copy SMILEScopy InChI
Affinity DataIC50: 62nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6837(indolocarbazole deriv. 13a | methyl 1-(2-{18-methy...)copy SMILEScopy InChI
Affinity DataIC50: 81nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6864(6-methyl-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0...)copy SMILEScopy InChI
Affinity DataIC50: 82nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BCNPubMed
LigandPNGBDBM6841(5-{2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]ethyl}...)copy SMILEScopy InChI
Affinity DataIC50: 90nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6862(6-fluoro-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0...)copy SMILEScopy InChI
Affinity DataIC50: 92nM EC50:  40nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BCNPubMed
LigandPNGBDBM6843(5-{2-[(2-hydroxyethyl)amino]ethyl}-18-methyl-3,13,...)copy SMILEScopy InChI
Affinity DataIC50: 95nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM2672(3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...)copy SMILEScopy InChI
Affinity DataIC50: 125nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BCNPubMed
LigandPNGBDBM6768(20-bromo-3-methyl-3,13,23-triazahexacyclo[14.7.0.0...)copy SMILEScopy InChI
Affinity DataIC50: 174nM EC50:  80nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BCNPubMed
LigandPNGBDBM6850(5-[3-(diethylamino)propyl]-18-methyl-3,13,18-triaz...)copy SMILEScopy InChI
Affinity DataIC50: 174nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6844(18-methyl-5-[2-(morpholin-4-yl)ethyl]-3,13,18-tria...)copy SMILEScopy InChI
Affinity DataIC50: 177nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6851(5-{3-[(4-hydroxycyclohexyl)amino]propyl}-18-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 216nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6856(6-methoxy-3,13,23-triazahexacyclo[14.7.0.0^{2,10}....)copy SMILEScopy InChI
Affinity DataIC50: 236nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BCNPubMed
LigandPNGBDBM6848(5-{3-[(2-hydroxyethyl)amino]propyl}-18-methyl-3,13...)copy SMILEScopy InChI
Affinity DataIC50: 266nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6839(18-methyl-5-[2-(piperazin-1-yl)ethyl]-3,13,18-tria...)copy SMILEScopy InChI
Affinity DataIC50: 301nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6847(18-methyl-5-[3-(4-methylpiperazin-1-yl)propyl]-3,1...)copy SMILEScopy InChI
Affinity DataIC50: 382nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6845(18-methyl-5-[2-(thiomorpholin-4-yl)ethyl]-3,13,18-...)copy SMILEScopy InChI
Affinity DataIC50: 403nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6849(18-methyl-5-[3-(morpholin-4-yl)propyl]-3,13,18-tri...)copy SMILEScopy InChI
Affinity DataIC50: 516nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6829(3-{2-[(2-hydroxyethyl)amino]ethyl}-6-methoxy-18-me...)copy SMILEScopy InChI
Affinity DataIC50: 527nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6834(3-{3-[(2-hydroxyethyl)amino]propyl}-6-methoxy-18-m...)copy SMILEScopy InChI
Affinity DataIC50: 732nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6854(6-chloro-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0...)copy SMILEScopy InChI
Affinity DataIC50: 914nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BCNPubMed
LigandPNGBDBM6830(3-{2-[(4-hydroxycyclohexyl)amino]ethyl}-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1.17E+3nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6859(7-bromo-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+3nM EC50:  70nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BCNPubMed
LigandPNGBDBM6857(6-bromo-20-methoxy-3,13,23-triazahexacyclo[14.7.0....)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BCNPubMed
LigandPNGBDBM6855(6-(trifluoromethyl)-3,13,23-triazahexacyclo[14.7.0...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BCNPubMed
LigandPNGBDBM6766(20-fluoro-3-methyl-3,13,23-triazahexacyclo[14.7.0....)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BCNPubMed
LigandPNGBDBM6831(1-(3-{6-methoxy-18-methyl-12,14-dioxo-3,13,18-tria...)copy SMILEScopy InChI
Affinity DataIC50: 3.05E+3nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6832(3-[3-(4-hydroxypiperidin-1-yl)propyl]-6-methoxy-18...)copy SMILEScopy InChI
Affinity DataIC50: 3.13E+3nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6827(3-{2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]ethyl}...)copy SMILEScopy InChI
Affinity DataIC50: 6.12E+3nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6878(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3n ...)copy SMILEScopy InChI
Affinity DataIC50: 8.90E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 10 uM ATP/[gamma-33P]ATP in a streptavidin coated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7KNXPubMed
LigandPNGBDBM6870(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3f ...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+4nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 10 uM ATP/[gamma-33P]ATP in a streptavidin coated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7KNXPubMed
LigandPNGBDBM6861(5-bromo-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^...)copy SMILEScopy InChI
Affinity DataIC50: 1.11E+4nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BCNPubMed
LigandPNGBDBM6833(6-methoxy-18-methyl-3-[3-(4-methylpiperazin-1-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 1.16E+4nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6860(6-bromo-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^...)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+4nM EC50:  70nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BCNPubMed
LigandPNGBDBM6828(6-methoxy-18-methyl-3-[2-(piperidin-1-yl)ethyl]-3,...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6835(6-methoxy-18-methyl-3-[3-(morpholin-4-yl)propyl]-3...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6836(6-methoxy-18-methyl-3-[3-(thiomorpholin-4-yl)propy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0CPWPubMed
LigandPNGBDBM6867(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3c ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 10 uM ATP/[gamma-33P]ATP in a streptavidin coated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7KNXPubMed
LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 10 uM ATP/[gamma-33P]ATP in a streptavidin coated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7KNXPubMed