Compile Data Set for Download or QSAR
Found 51 of ic50 for UniProtKB: P49448
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109087(US10793535, Cmpd ID 671 | US8604016, 671 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109082(US10793535, Cmpd ID 666 | US8604016, 666 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109086(US10793535, Cmpd ID 727 | US8604016, 670 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM108867(US10793535, Cmpd ID 447 | US8604016, 447 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109074(US10793535, Cmpd ID 658 | US8604016, 658 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109018(US10793535, Cmpd ID 600 | US8604016, 600 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM108759(US10793535, Cmpd ID 339 | US8604016, 339 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM108856(US10793535, Cmpd ID 436 | US8604016, 436 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM108739(US10793535, Cmpd ID 318 | US8604016, 318 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109003(US10793535, Cmpd ID 585 | US8604016, 585 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109089(US10793535, Cmpd ID 673 | US8604016, 673 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM108951(US10793535, Cmpd ID 533 | US8604016, 533 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109077(US10793535, Cmpd ID 661 | US8604016, 661 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109078(US10793535, Cmpd ID 662 | US8604016, 662 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109079(US10793535, Cmpd ID 663 | US8604016, 663 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109054(US10793535, Cmpd ID 636 | US8604016, 636 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109090(US10793535, Cmpd ID 674 | US8604016, 674 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109034(US10793535, Cmpd ID 616 | US8604016, 616 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109032(US10793535, Cmpd ID 614 | US8604016, 614 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109084(US10793535, Cmpd ID 668 | US8604016, 668 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109033(US10793535, Cmpd ID 615 | US8604016, 615 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109088(US10793535, Cmpd ID 672 | US8604016, 672 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109075(US10793535, Cmpd ID 659 | US8604016, 659 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM108715(US10793535, Cmpd ID 295 | US8604016, 295 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM383200(US10278968, Compound 728 | US10793535, Cmpd ID 728)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM383202(US10278968, Compound 730 | US10793535, Cmpd ID 730)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109004(US10793535, Cmpd ID 586 | US8604016, 586 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM383201(US10278968, Compound 729 | US10793535, Cmpd ID 729)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM383193(US10278968, Compound 721 | US10793535, Cmpd ID 721)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM383192(US10278968, Compound 720 | US10793535, Cmpd ID 720)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109085(US10793535, Cmpd ID 669 | US8604016, 669)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109086(US10793535, Cmpd ID 727 | US8604016, 670 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM383194(US10278968, Compound 722 | US10793535, Cmpd ID 722)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109076(US10793535, Cmpd ID 660 | US8604016, 660 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM383190(US10278968, Compound 718 | US10793535, Cmpd ID 718)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM383191(US10278968, Compound 719 | US10793535, Cmpd ID 719)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM383189(US10278968, Compound 717 | US10793535, Cmpd ID 717)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM383195(US10278968, Compound 723 | US10793535, Cmpd ID 723)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM383197(US10278968, Compound 725 | US10793535, Cmpd ID 725)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM108715(US10793535, Cmpd ID 295 | US8604016, 295 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM108773(US10793535, Cmpd ID 354 | US8604016, 354 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM50400050(CHEMBL2177757 | US10793535, Cmpd ID 1 | US11191732...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM383196(US10278968, Compound 724 | US10793535, Cmpd ID 724)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM108759(US10793535, Cmpd ID 339 | US8604016, 339 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM108739(US10793535, Cmpd ID 318 | US8604016, 318 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM383188(US10278968, Compound 715 | US10793535, Cmpd ID 715)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM50400050(CHEMBL2177757 | US10793535, Cmpd ID 1 | US11191732...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109073(US10793535, Cmpd ID 726 | US8604016, 657 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM109073(US10793535, Cmpd ID 726 | US8604016, 657 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences, Inc.

US Patent
LigandPNGBDBM108822(US10793535, Cmpd ID 402 | US8604016, 402 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2KV5US Patent
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